Radiology:二胎时代到来,MR成像可用来评估胎儿生长受限!

2017-07-15 shaosai MedSci原创

二胎时代到来,临床工作中对于孕产妇的检查越来越不拘泥于超声检查,MR检查技术的更新越来越能满足临床对于患者检查目的的需要。研究人员利用氧增强和血氧水平依赖性(BOLD)磁共振(MR)成像参数评价在正常胎儿和胎儿生长限制(FGR)的孕妇中胎盘的差异,进而探究MR对FGR检出率的价值,并将结果发表在影像学权威杂志Radiology上。

二胎时代到来,临床工作中对于孕产妇的检查越来越不拘泥于超声检查,MR检查技术的更新越来越能满足临床对于患者检查目的的需要。研究人员利用氧增强和血氧水平依赖性(BOLD)磁共振(MR)成像参数评价在正常胎儿和胎儿生长限制(FGR)的孕妇中胎盘的差异,进而探究MR对FGR检出率的价值,并将结果发表在影像学权威杂志Radiology上。

本病例对照研究自2010年10月至2015年10月共纳入了28例非复杂妊娠妇女(个体化出生体重比例[IBR]>第20百分位数和生产时孕周> 37周),23例孕妇伴随FGR(IBR <5百分位数和超声检查结果异常[US])并行 MR成像。给予受试者呼吸空气或氧气来分析定量胎盘纵向R1(1 / T1)和横向R2 *(1 / T2 *)的差异。ΔR1为吸氧后的氧分压变化(ΔPo2)。采用非配对T检验分析两组间干预差异。以胎龄作为协变量建立logistic回归诊断模型。

正常妊娠孕妇胎盘平均基线R1和R2 *(R1:0.59s-1,95%[CI]:0.58 s-1,0.60秒-1; R2 *:17 s-1,95%CI:14 s-1,20 s-1)与合并FGR妊娠的孕妇(R1:0.63 s-1,95%CI:0.62 s-1 0.65 s-1; R2 *:26 s-1,95% CI:22 s-1,32 s-1)(P <.0001)。在所有受试者中ΔR1与胎龄显着负相关(P <0.0001),FGR组的ΔR1要明显低于正常孕妇组,差异有统计学意义(P = .003)。FGR与正常妊娠受试者的ΔPo2、 基线 R1和R2*曲线下面积(ROC)为0.91(95%CI:0.82,0.99)。

正常妊娠和合并重度FGR孕妇的R1,R2 *和ΔPo2间差异有显着性。利用MR成像参数有助于识别与FGR相关的胎盘功能障碍,并且在临床工作中有助于准确鉴别FGR和因胎龄小而体积小的正常胎儿。

原始出处:

Emma Ingram, David Morris, Josephine Naish,et al,MR Imaging Measurements of Altered Placental Oxygenation in Pregnancies Complicated by Fetal Growth Restriction. Radiology. 2017.DOI:10.1148/radiol.2017162385

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    2017-07-15 惠映实验室

    学习了,谢谢

    0

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    2017-07-15 邓启付

    MRI评价胎儿发育有很大优势

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1417951, encodeId=76e5141e95173, content=<a href='/topic/show?id=70988361670' target=_blank style='color:#2F92EE;'>#胎儿生长受限#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83616, encryptionId=70988361670, topicName=胎儿生长受限)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=073b3313558, createdName=fanweitanzhen, createdTime=Mon Jul 17 03:09:00 CST 2017, time=2017-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480222, encodeId=788c1480222be, content=<a href='/topic/show?id=d47d2404839' target=_blank style='color:#2F92EE;'>#二胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24048, encryptionId=d47d2404839, topicName=二胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4a257628025, createdName=ms1065684921169360, createdTime=Mon Jul 17 03:09:00 CST 2017, time=2017-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222620, encodeId=9919222620b5, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Jul 15 15:27:40 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222586, encodeId=7f722225864f, content=MRI评价胎儿发育有很大优势, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sat Jul 15 12:24:06 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222583, encodeId=24692225833c, content=好的,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sat Jul 15 12:20:10 CST 2017, time=2017-07-15, status=1, ipAttribution=)]
    2017-07-15 Drhzm308

    好的,学习了

    0

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