NEJM:黑头粉刺样痣

2015-07-07 MedSci MedSci原创

一名19岁的男子称在其左侧锁骨区域出现先天性的皮肤病变(如图A所示),视诊可见扩张毛囊皮脂腺开口与角质栓紧密排列,类似于经典粉刺(如图B)。这些皮脂腺开口均沿左锁骨呈线性分布和延伸到背上,形成了巧妙的色素沉着带,但没有明显的界限。经体格检查,该男子没有出现相关的神经系统异常或骨骼畸形的现象。取皮肤活组织病理学检查,可见典型的、分组的和扩张毛囊口充满角蛋白,但未见头发轴。根据该男子的临床症状及检查结

一名19岁的男子称在其左侧锁骨区域出现先天性的皮肤病变(如图A所示),视诊可见扩张毛囊皮脂腺开口与角质栓紧密排列,类似于经典粉刺(如图B)。这些皮脂腺开口均沿左锁骨呈线性分布和延伸到背上,形成了巧妙的色素沉着带,但没有明显的界限。




经体格检查,该男子没有出现相关的神经系统异常或骨骼畸形的现象。取皮肤活组织病理学检查,可见典型的、分组的和扩张毛囊口充满角蛋白,但未见头发轴。

根据该男子的临床症状及检查结果,该男子最终被确诊为患有黑头粉刺样痣。

黑头粉刺样痣,也称毛囊皮脂腺单位的一种错构瘤,是出生即有或在儿童早期发育过程中发生的。其最常见的发病部位是面部、颈部、胸部和上臂,在青春期时会出现加速增长的现象。目前,有人认为患黑头粉刺样痣可能会导致中枢神经系统异常或白内障,但其具体的病理生理尚不明确,怀疑是该病并发炎症或继发感染等原因导致。

对于此病,目前可选择的治疗方案有局部治疗、激光治疗和手术治疗。但由于该男子拒绝进一步干预,只能对其继续进行临床观察。

原文出处:

Anisha Bhullar, M.R.C.P., and Norashikin Shamsudin, Adv.M.Derm.IMAGES IN CLINICAL MEDICINE. Nevus Comedonicus.N Engl J Med 2015; 372:2541 DOI: 10.1056/NEJMicm1406555z

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    2024-01-05 ms1000002072462949 来自广东省

    厉害咯

    0

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    2015-08-28 gdsun
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    2015-07-09 yese
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    2015-07-09 owlhealth

    真多

    0

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    2015-07-08 medcardio

    病例特殊,不知道机制

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2179508, encodeId=ebd321e95088c, content=厉害咯, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4afc5377764, createdName=ms1000002072462949, createdTime=Fri Jan 05 23:04:48 CST 2024, time=2024-01-05, status=1, ipAttribution=广东省), GetPortalCommentsPageByObjectIdResponse(id=1655124, encodeId=e2191655124eb, content=<a href='/topic/show?id=43a9e6188a0' target=_blank style='color:#2F92EE;'>#粉刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76188, encryptionId=43a9e6188a0, topicName=粉刺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=890524636984, createdName=gdsun, createdTime=Fri Aug 28 16:40:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487609, encodeId=3762148e60921, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Jul 09 11:40:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31769, encodeId=282a31e699e, content=真多, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Jul 09 07:26:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31696, encodeId=ccb531696cc, content=病例特殊,不知道机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Wed Jul 08 15:12:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31570, encodeId=8ab9315e014, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:11:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31490, encodeId=16a331490a8, content=被图片给吓到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Wed Jul 08 00:53:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2015-07-08 huaxipanxing

    看看

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2179508, encodeId=ebd321e95088c, content=厉害咯, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4afc5377764, createdName=ms1000002072462949, createdTime=Fri Jan 05 23:04:48 CST 2024, time=2024-01-05, status=1, ipAttribution=广东省), GetPortalCommentsPageByObjectIdResponse(id=1655124, encodeId=e2191655124eb, content=<a href='/topic/show?id=43a9e6188a0' target=_blank style='color:#2F92EE;'>#粉刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76188, encryptionId=43a9e6188a0, topicName=粉刺)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=890524636984, createdName=gdsun, createdTime=Fri Aug 28 16:40:00 CST 2015, time=2015-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487609, encodeId=3762148e60921, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Jul 09 11:40:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31769, encodeId=282a31e699e, content=真多, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Jul 09 07:26:00 CST 2015, time=2015-07-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31696, encodeId=ccb531696cc, content=病例特殊,不知道机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Wed Jul 08 15:12:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31570, encodeId=8ab9315e014, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed Jul 08 12:11:00 CST 2015, time=2015-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=31490, encodeId=16a331490a8, content=被图片给吓到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Wed Jul 08 00:53:00 CST 2015, time=2015-07-08, status=1, ipAttribution=)]
    2015-07-08 保守主义

    被图片给吓到了

    0