JAMA Surg:2012年后,前列腺活检和切除术在下降

2016-11-09 MedSci MedSci原创

研究表明,USPSTF在2012年提出反对前列腺特异性抗原筛查后,前列腺特异性抗原筛查显著下降。研究目的是确定2012 USPSTF提出的这项建议对前列腺癌诊断与治疗的实践模式的下游效应。研究中的手术记录来自美国泌尿科学委员会,并识别至少进行一次前列腺活检的泌尿科医生(n = 5173)或至少进行一次根治性前列腺切除术(RP)的泌尿科医生(n = 3748)。2012 USPSTF后,每位泌尿科医

研究表明,USPSTF在2012年提出反对前列腺特异性抗原筛查后,前列腺特异性抗原筛查显著下降。

研究目的是确定2012 USPSTF提出的这项建议对前列腺癌诊断与治疗的实践模式的下游效应。

研究中的手术记录来自美国泌尿科学委员会,并识别至少进行一次前列腺活检的泌尿科医生(n = 5173)或至少进行一次根治性前列腺切除术(RP)的泌尿科医生(n = 3748)。

2012 USPSTF后,每位泌尿科医生的前列腺活检中位数下降,从29到21(四分位数范围[IQR}, 12-34; P < .001)。校正混杂因素后,下降幅度为28.7%(参数估计,−0.25; SE, 0.03; P < .001)。

2012 USPSTF后,每位泌尿科医生的RP量中位数从7 (IQR, 3-15)下降到6 (IQR, 2-12) (P < .001),校正混杂因素后,下降幅度为16.2%(参数估计, −0.15; SE, 0.05; P = .003)。

继2012 USPSTF提出后,前列腺活检和RP量明显下降。还需要更多的研究,评价2012 USPSTF的长期后果。

原始出处:

Joshua A. Halpern, MD, MS1; Jonathan E. Shoag, MD1; Amanda S. Artis, MS, MPH2; et alNational Trends in Prostate Biopsy and Radical Prostatectomy Volumes Following the United States Preventative Services Task Force Guidelines Against Prostate-Specific Antigen Screening JAMA Surg. Published online November 2, 2016. doi:10.1001/jamasurg.2016.3987 


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    2016-11-11 inter158

    这个翻译好像不够地道啊

    0

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    2016-11-11 smlt2008