盘点:Neurology 8月8日刊研究精选

2017-08-10 zhangfan MedSci原创

Neurology 8月8日刊研究精选



【1】封面文章——烟雾病Percheron动脉瘤病例


Armen J. Moughamian等报道了罕见的烟雾病Percheron动脉瘤病例。50岁日本女性,影像学检查示左侧丘脑区域的脑出血。CT血管造影后的影像显示出与烟雾病(Moyamoya病)一致的改变,同时在患者的出血灶内可以看到“点状征”样改变。进一步检查证实CT“点状征”实际上是Percheron动脉产生的假性动脉瘤。烟雾病患者可合并发生颅内动脉瘤,常发生在威利斯环,外周动脉远端或烟雾血管,其发生率约3:1:1.1。患者的动脉瘤位于丘脑穿通动脉,这种情况很少见,并且目前尚无关于烟雾病患者Percheron动脉发生动脉瘤的报道。

【2】不明原因脑栓塞患者患者年龄以及性别特异性分析


近日研究人员在不明原因脑栓塞(ESUS)患者人群中探讨了与缺血性脑卒中复发和死亡风险相关的年龄和性别特征。研究发现,各年龄段、每100患者年的缺血性脑卒中以及短暂性脑缺血复发或死亡如下:60岁以下人群2.46和1.01,60-80岁人群5.76和5.23,80岁以上人群7.88和11.58;性别方面,女性3.53和3.48,男性4.49和3.98。对于<60 人群,60-80岁人群以及>80人群的缺血性脑卒中以及短暂性脑缺血10年累计复发率分别为14.0%,47.9%和37.0%,10年累计死亡率分别为6.4%,40.6%和100%。

【3】机械取栓后血压水平对大血管闭塞卒中患者预后的影响


近日研究人员评估了机械取栓后血压变化对大血管闭塞患者早期结局影响。研究发现,机械取栓后首个24小时内最大动脉压增加10mmHg与患者3个月预后的独立相关性较低,但与患者3个月死亡率升高相关。血压控制在160/90mmHg目标范围与患者3个月死亡率降低独立相关。

【4】CT平扫对脑出血范围扩大的预测作用


近日研究人员对CT平扫对脑血肿范围扩大的预测作用进行了考察。研究发现所有CT检查的相关症状(血管内壁水肿消失,黑洞征,漩涡征,混合征,血肿密度以及形状不规则)均可有效预测脑血肿范围扩大,其准确度范围61%-78%并且存在良好的可信性。但CT指标与强化降压治疗临床收益之间无相关性。

【5】帕金森患者磷酸二酯酶4表达减


近日研究人员考察了磷酸二酯酶4的体内表达与帕金森病患者认知症状的相关性。研究发现帕金森患者精神运动速度、情景记忆、空间工作记忆和执行功能显著下降,患者尾状核、丘脑、下丘脑和皮质的磷酸二酯酶4表达分别减少28%、23%、32%以及16%。帕金森患者纹状体-丘脑-皮质回路磷酸二酯酶4减少与空间工作记忆衰退相关。

【6】脊髓型颈椎病脱髓鞘程度评估


近日研究人员利用髓鞘水成像和电生理学技术对脊髓型颈椎病脱髓鞘程度进行了评价。研究发现脊髓型颈椎病患者其T2信号强度、压缩比、脊髓受压和椎管受限存在显著异常,但体感诱发电位以及髓鞘水含量无显著异常。部分体感诱发电位异常患者其髓鞘水含量减少,程度与体感诱发电位的潜伏期相关。

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    2018-04-20 yinhl1978
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    2017-08-30 虈亣靌

    不错的.学习了.谢谢分享!

    0

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    2017-08-19 虈亣靌

    讲解的非常好,值得学习

    0

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    2017-08-12 虈亣靌

    不错的,学习了!谢谢分享!

    0

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    2017-08-11 hfuym10906

    学习了学习了学习了学习了

    0

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    2017-08-11 meiliwuxian

    非常不错

    0

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    2017-08-10 tomoyo89

    每日一学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2000068, encodeId=5664200006815, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Apr 20 14:45:00 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238738, encodeId=4c1e238e3826, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Aug 30 17:57:26 CST 2017, time=2017-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235153, encodeId=481d2351533f, content=讲解的非常好,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 19 19:14:03 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232935, encodeId=6ec623293546, content=不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 12 19:53:21 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232356, encodeId=ebfb2323560e, content=学习了学习了学习了学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuIjZYTAgkEia1SFuoeAByVaQC8uXegibpJEV2Q7SqhpDINJicNiaU5pYicYmy5WsI8l5hDribViac2A1BQ9/0, createdBy=c36f1724608, createdName=hfuym10906, createdTime=Fri Aug 11 07:21:10 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232345, encodeId=ae12232345d9, content=非常不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Fri Aug 11 06:59:53 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232282, encodeId=439e232282cd, content=每日一学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM5dnicvDOticughRdDibueiaibRzxp5icvQ7EXr3aSxIIfpGFlQ/0, createdBy=e3031710362, createdName=tomoyo89, createdTime=Thu Aug 10 23:39:18 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232242, encodeId=5f6f23224286, content=学了。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Thu Aug 10 22:05:49 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232204, encodeId=d95923220477, content=部分体感诱发电位异常患者其髓鞘水含量减少,程度与体感诱发电位的潜伏期相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Aug 10 17:04:03 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-10 135****7952平儿

    学了。。。。。。。。

    0

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    2017-08-10 有备才能无患

    部分体感诱发电位异常患者其髓鞘水含量减少,程度与体感诱发电位的潜伏期相关。

    0

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