Hypertension:儿童时期的社会经济状态与成年动脉僵硬度之间有关吗?

2017-08-16 xing.T MedSci原创

总之,该研究可以观察到儿童时期家庭SES水平与成年后较低的动脉僵硬度相关。该研究结果表明需要对较低SES家庭的孩子加以特别注意以预防心脏疾病。

越来越多的证据支持社会经济因素在动脉粥样硬化性心血管疾病发展中的重要性。然而,儿童时期的社会经济状态(SES)与成年时动脉僵硬度之间的相关性尚未明确。近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员旨在明确儿童较高的家庭SES水平是否与成年后动脉僵硬度降低有关。

研究人员采用了年轻芬兰人纵向研究的数据进行分析。该样本包括了2566名参与者,这些参与者具有1980年3至18岁期间的家庭SES数据,并且在成年后21后27岁进行动脉脉搏波传导速度与颈动脉扩张性测量。

研究人员发现儿童时期较高的SES水平与成年时较低的动脉僵硬度相关;在调整了年龄、性别和传统的儿童心血管危险因素后的多变量分析中,儿童时期较高的SES水平的参与者成年时具有较高的颈动脉扩张性(β值±SE为0.029±0.0089%/10mmHg;P=0.001)和较低的脉搏波速度(β值±SE为-0.062±0.022米/秒;P=0.006)。在进一步调整参与者的成年时的SES后,这一相关性仍有显著(颈动脉扩张性的β值±SE,0.026±0.010%/10mmHg;P=0.01;脉搏波速度的β值±SE为-0.048±0.023米/秒;P=0.04),但在调整了成年心脏代谢风险因素后,相关性有所减弱(颈动脉扩张性的β值±SE为0.015±0.008%/10mmHg;P=0.08;脉搏波速度的β值±SE为-0.019±0.02米/秒;P=0.38)。

总之,该研究可以观察到儿童时期家庭SES水平与成年后较低的动脉僵硬度相关。该研究结果表明需要对较低SES家庭的孩子加以特别注意以预防心脏疾病。

原始出处:

Elina Puolakka,et al. Childhood Socioeconomic Status and Arterial Stiffness in Adulthood The Cardiovascular Risk in Young Finns Study.Hypertension.2017. https://doi.org/10.1161/HYPERTENSIONAHA.117.09718

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level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Sep 07 11:27:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1805566, encodeId=cc251805566c4, content=<a href='/topic/show?id=af59e83582d' target=_blank style='color:#2F92EE;'>#经济状态#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78358, encryptionId=af59e83582d, topicName=经济状态)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e572480, createdName=旅苦化文_208, createdTime=Sun May 20 11:27:00 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234769, encodeId=72a9234e6911, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Aug 18 14:50:39 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501194, encodeId=605215011944d, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546734, encodeId=02aa1546e340e, content=<a href='/topic/show?id=de1233215db' target=_blank style='color:#2F92EE;'>#动脉僵硬#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33215, encryptionId=de1233215db, topicName=动脉僵硬)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b48f13938152, createdName=dlwang_26703131, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546797, encodeId=84571546e9785, content=<a href='/topic/show?id=96a0332168b' target=_blank style='color:#2F92EE;'>#动脉僵硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33216, encryptionId=96a0332168b, topicName=动脉僵硬度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eb8013942519, createdName=1696533704_45270458, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616717, encodeId=a2921616e17c0, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=)]
    2017-09-07 feather89
  5. 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  6. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546734, encodeId=02aa1546e340e, content=<a href='/topic/show?id=de1233215db' target=_blank style='color:#2F92EE;'>#动脉僵硬#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33215, encryptionId=de1233215db, topicName=动脉僵硬)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b48f13938152, createdName=dlwang_26703131, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546797, encodeId=84571546e9785, content=<a href='/topic/show?id=96a0332168b' target=_blank style='color:#2F92EE;'>#动脉僵硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33216, encryptionId=96a0332168b, topicName=动脉僵硬度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eb8013942519, createdName=1696533704_45270458, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616717, encodeId=a2921616e17c0, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Aug 18 07:27:00 CST 2017, time=2017-08-18, status=1, ipAttribution=)]
    2017-08-18 清风拂面

    谢谢分享,学习了

    0

  7. 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