肺结核、非结核分枝杆菌肺病、支原体肺炎丨影像表现

2022-07-23 熊猫放射 熊猫放射

分枝杆菌和支原体

分枝杆菌和支原体

Mycobacteria and Mycoplasma

 

结核

Tuberculosis(TB)

 

  • 结核分枝杆菌空气传播感染

 

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(左) 22岁男性,咳嗽和发热。PA胸片显示左肺上叶实变伴空洞和腔内气液平面。痰中抗酸杆菌阳性,培养出结核分枝杆菌。
(右) 一位患有肺结核的年轻女性,PA胸片显示左肺上叶结节和斑片影。

 

 

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(左) 同一患者2年后的PA胸片显示左肺上叶结节性病变和空洞,较前进展。抗结核治疗不当或不完全的病人可能发展为耐药性肺结核。

 (右) 再次应用抗结核药物治疗后轴位CT显示左肺尖结节改善但持续存在,不能排除疾病的活动性。

 

 

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(左) 49岁活动性肺结核患者的胸片显示左肺上叶空洞和双肺大量小结节,继发于肺部感染的支气管内播散。这类病人是有传染性的。

(右) 轴位CT显示右肺上叶小叶中心结节和树芽征,以及上叶支气管扩张。

 

 

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(左) 同一患者,轴位CT显示右肺上叶空洞并壁结节,周围有毛细支气管炎和树芽征。虽然细菌、病毒和真菌感染可引起毛细支气管炎,但空洞的存在高度提示TB。

(右) 右肺下叶支气管壁明显增厚和毛细支气管炎。空洞、毛细支气管炎和支气管壁增厚与活动性肺结核相一致。

 

 

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(左) 海洛因成瘾者,发热。PA胸片显示右肺上叶实变并空气支气管征。患者对抗菌治疗无反应,支气管镜检查诊断为活动性肺结核。

(右) 同一患者,CT显示右肺上叶不均匀实变,伴磨玻璃影,纵隔淋巴结肿大。原发性肺结核与免疫损害有关,并不一定意味着最初的感染。

 

 

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(左) 男性,发热和胸痛。PA胸片显示左肺上叶实变,左肺门及纵隔肿大淋巴结。与淋巴结增大相关的肺实变应提示非典型感染,包括TB。

(右) 同一患者,纵隔窗示左肺上叶实变,左肺门及纵隔肿大淋巴结,中央低密度,周围边缘强化,提示坏死。

 

 

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(左)  51岁女性,肾移植术后并发粟粒性结核。轴位CT显示左上纵隔增大淋巴结伴中心低密度和外周强化。

(右) 同一患者,双肺散在随机分布的边界清楚的2-3mm粟粒性结节,在X线片上不可见。粟粒性肺结核通常影响免疫功能低下的患者,可能与肺外结核有关。

 

 

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(左) 年轻男性,患有结核性脓胸,发热和左胸痛。胸片显示左侧胸腔积液或胸膜增厚,邻近的左胸壁软组织不对称增厚。

(右) 同一患者,CT显示左侧包裹性胸腔积液伴胸膜增厚、钙化、有强化。可见左侧椎旁脓肿并邻近肋骨破坏。

 

 

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(左) 男性患者,无症状,既往有结核性脓胸并发纤维胸。PA胸片显示右肺非对称性体积缩小,右侧胸膜致密钙化。多年来一直稳定,痰培养为阴性,可认为是非活动性疾病。

(右) 42岁女性,无症状,既往有肺结核,胸片显示稳定的右肺尖多发钙化结节,与已治愈的结核瘤一致。

 

 

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(左) 41岁活动性肺结核患者,PA胸片显示双肺上叶不均匀实变、空腔及周围的毛细支气管炎,与活动性疾病相一致。注意上叶体积减少和双侧膈上尖峰征(弯箭)。

(右) 一例痰阴性的治愈的肺结核患者,冠状CT显示双肺上叶容积减少,伴有支气管扩张和结构扭曲,代表先前结核病的后遗症。

 

 

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(左) 肺结核痰阴性患者,胸片显示左肺容积明显减少,纵隔左移,支气管扩张,右肺过度充气和钙化的结核瘤。

(右) 先前接受过肺结核治疗的患者,胸片显示左半胸密度增高,内有含空气的“玻璃球”,右肺上叶结构变形和体积缩小。

 

 

非结核分枝杆菌感染

Nontuberculous Mycobacterial Infection

 

  • 非结核分枝杆菌感染 (NTMBI)

  • 鸟-胞内分枝杆菌复合体 (MAC)

  • NTMBI,最常见的由MAC引起

 

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(左) 35岁女性,因治疗系统性红斑狼疮而服用硫唑嘌呤。PA胸片显示双肺纤维空洞性肺炎,体积缩小,上叶为著。支气管肺泡灌洗标本培养显示MAC。

(右) 慢性支气管扩张性MAC感染患者,可见支气管扩张、树芽征,高通透性低灌注肺,提示小气道疾病引起的空气潴留。

 

 

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(左) 60岁男性,无症状,右肺上叶结节,内见微小的非特异性钙化灶。细针穿刺活检标本可见蟾蜍分枝杆菌生长。

(右) 慢性淋巴细胞白血病患者,双肺弥漫性粟粒性肺结节,继发于MAC感染。CT表现提示血源性感染扩散至肺部。

 

 

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(左) 患者,咳嗽。左肺上野孤立的空腔,壁略厚。支气管镜标本培养证实了MAC感染。

(右) 慢性肺气肿患者,冠状CT显示双肺上叶空洞样病变,伴有严重的上叶体积缩小、肺门回缩和结构变形。重复培养龟分枝杆菌呈阳性。

 

 

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(左) 62岁男性,慢性堪萨斯分枝杆菌肺部感染。双肺巨大的菌丝体瘤,表现为双肺尖空洞样病变,腔内软组织肿块,洞壁较厚,邻近胸膜增厚,胸膜外脂肪水肿 (活动性感染的结果)。

(右) 60岁男性,肺气肿,胸片显示右肺体积小,由于慢性MAC感染,同侧严重的纤维空洞性肺病,与肺结核没有区别。

 

 

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(左) 75岁女性,支气管扩张型NTMBI。轴位HRCT显示右肺中叶和左肺舌段容积减少、支气管扩张和支气管壁增厚。左肺下叶轻度支气管扩张。

(右) MAC过敏患者,双肺磨玻璃影、磨玻璃结节,马赛克征。肺透亮度增高和空气潴留提示小气道疾病。

 

 

支原体肺炎

Mycoplasma Pneumonia

 

  • 肺炎支原体引起的肺炎

  • 儿童和年轻人最常见的非典型社区获得性肺炎

 

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(左) 19岁患者,发热、咳嗽和头痛。胸片示心脏后实变影,主动脉旁界面模糊,符合左肺下叶肺炎。

(右) 同一患者,侧位胸片证实左肺下叶实变。痰肺炎支原体PCR阳性。支原体是年轻人社区获得性肺炎的常见原因。

 

 

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(左) 发热和咳嗽患者,胸片显示右中、下肺野斑片状实变影,左下肺野可见网状结节影。

(右) 轴位CT显示右肺下叶部分实变,双肺下叶广泛小叶中心结节和树芽征。痰肺炎支原体PCR检测阳性。支原体肺炎好发于下叶。

 

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    2022-07-29 amy0559
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