JAMA Surg:老年患者术后丧失独立性是术后再入院和出院后死亡的危险因素

2016-10-18 MedSci MedSci原创

老年人在手术后的不良事件风险增加。丧失独立性(LOI),定义为功能或移动的下降,需要在家里增加护理,或出院到非家里的目的地,是一个重要的以病人为中心的测量结果。本回顾性队列研究纳入9972例大于等于65岁的患者,已知基线功能、移动能力和生活情况,从2014年1月到2014年12月参与美国外科医师学会国家老年外科质量改进计划试点项目,共有4895例患者被排除在外,因为他们完全非独立,按美国麻醉医师协

老年人在手术后的不良事件风险增加。丧失独立性(LOI),定义为功能或移动的下降,需要在家里增加护理,或出院到非家里的目的地,是一个重要的以病人为中心的测量结果。

本回顾性队列研究纳入9972例大于等于65岁的患者,已知基线功能、移动能力和生活情况,从2014年1月到2014年12月参与美国外科医师学会国家老年外科质量改进计划试点项目,共有4895例患者被排除在外,因为他们完全非独立,按美国麻醉医师协会的分类为5类,接受骨科或脊柱手术,或者出院前死亡。

在这项研究中的5077例患者中,有2736例(53.9%)为女性,3876例(76.3%)为白人,平均(SD)年龄75 (7) 岁。这个队列,LOI随年龄的增加而增加;65岁至74岁,LOI发生情况为1386/2780例患者(49.9%),75岁到84岁为1162/1726 (67.3%),5岁以上479/571 (83.9%)(P < .001)。

再入院发生517例(10.2%)。在风险调整模型,LOI与再入院密切相关(比值比,1.7; 95% CI, 1.4-2.2),与术后并发症密切相关(比值比,6.7;95% CI,4.9-9.0)。

出院后死亡69例(1.4%)。经风险调整后,LOI是与出院后死亡相关的最强因子(比值比,6.7;95% CI,2.4-19.3)。术后并发症与出院后死亡无显著相关性。

丧失独立性是以病人为中心的结果,与术后再入院和出院后死亡相关。最小化LOI的临床举措将对改善老年患者的手术护理至关重要。

原始出处:

Julia R. Berian, MD1,2; Sanjay Mohanty, MD, MS1,3; Clifford Y. Ko, MD, MS, MSHS1,4; et al.Association of Loss of Independence With Readmission and Death After Discharge in Older Patients After Surgical Procedures. JAMA Surg. 2016;151(9):e161689. doi:10.1001/jamasurg.2016.1689

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1798098, encodeId=21ce1e980988b, content=<a href='/topic/show?id=e4d66813043' target=_blank style='color:#2F92EE;'>#独立性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68130, encryptionId=e4d66813043, topicName=独立性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b78f2500065, createdName=12498761m56暂无昵称, createdTime=Sat Sep 30 02:31:00 CST 2017, time=2017-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155195, encodeId=050615519520, content=丧失独立性是以病人为中心的结果,与术后再入院和出院后死亡相关。最小化LOI的临床举措将对改善老年患者的手术护理至关重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Nov 12 08:17:37 CST 2016, time=2016-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152992, encodeId=0ac015299265, content=一篇高质量的文章,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b2a1732571, createdName= gospel007, createdTime=Wed Nov 02 23:32:10 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151808, encodeId=77ca15180801, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Oct 29 00:52:39 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-11-12 ylzr123

    丧失独立性是以病人为中心的结果,与术后再入院和出院后死亡相关。最小化LOI的临床举措将对改善老年患者的手术护理至关重要。

    0

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    2016-11-02 gospel007

    一篇高质量的文章,学习了。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1798098, encodeId=21ce1e980988b, content=<a href='/topic/show?id=e4d66813043' target=_blank style='color:#2F92EE;'>#独立性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68130, encryptionId=e4d66813043, topicName=独立性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b78f2500065, createdName=12498761m56暂无昵称, createdTime=Sat Sep 30 02:31:00 CST 2017, time=2017-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155195, encodeId=050615519520, content=丧失独立性是以病人为中心的结果,与术后再入院和出院后死亡相关。最小化LOI的临床举措将对改善老年患者的手术护理至关重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Nov 12 08:17:37 CST 2016, time=2016-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152992, encodeId=0ac015299265, content=一篇高质量的文章,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b2a1732571, createdName= gospel007, createdTime=Wed Nov 02 23:32:10 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151808, encodeId=77ca15180801, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Oct 29 00:52:39 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-10-29 忠诚向上

    好好学习

    0