Stroke:短暂性脑缺血发作中孤立性非典型短暂性症状的临床意义!

2017-05-10 xing.T MedSci原创

由此可见,短暂性缺血发作的诊断应考虑和研究孤立性非典型TS患者。

与典型的短暂性症状(TS)相反,非典型的TS,如局部感觉障碍、构音障碍、眩晕、步态不稳、不寻常的皮层视觉缺失、复视,通常不被归类为短暂性脑缺血发作的症状,当它们单独发生时,其临床意义经常被否认。

近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员对其所在的短暂性脑缺血发作诊所(2003-2008年)连续就诊的近期TS患者进行了系统的脑、动脉和心脏检查。在排除主要鉴别诊断后,研究人员比较了孤立的典型或非典型TS患者和非孤立的TS患者脑成像图像上近期脑梗死的患病率、主要调查结果(症状性颅内或颅外动脉狭窄≥50%、颈动脉夹层和主要来源于心脏的栓塞)和主要血管事件的1年风险。

在1850例可能或明确的缺血性诊断患者中,有798例(43.1%)患者为孤立性TS:621例为典型TS患者(33.6%)和177例为非典型TS患者(9.6%)。脑成像图像上急性脑梗死发生情况在孤立的非典型TS患者和典型TS患者之间类似,但是比非孤立的TS患者更不频繁,观察的发生率分别为10%、11.5%和15.3%(P<0.0001)。主要调查结果分在18.1%、26.4%和26.3%的患者中可以观察到(P=0.06)。3组间大血管事件的1年风险差异无统计学意义。

由此可见,短暂性缺血发作的诊断应考虑和研究孤立性非典型TS患者。

原始出处:

Philippa C. Lavallée,et al. Clinical Significance of Isolated Atypical Transient Symptoms in a Cohort With Transient Ischemic Attack.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.016743

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  5. 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content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-12 jxrzshh
  6. 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content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 尹玉伟

    学习了……厉害几次

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 meiliwuxian

    非常不错!学习了

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 jacob9231

    谢谢分享,学习了

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 tanxingdoctor

    学习了,谢谢分享

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-10 1e0f8808m18(暂无匿称)

    短暂脑缺血发作,应引起重视。

    0

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