Eur Respir J:母乳喂养、母亲哮喘和婴幼儿一岁时哮鸣音有何关系?

2017-06-21 xing.T MedSci原创

由此可见,在哮喘母亲生出的婴儿中,母乳喂养似乎能以剂量依赖的方式保护哮鸣音。

母乳喂养对呼吸系统健康的影响尚不确定,尤其是当母亲患有哮喘的时候。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,研究人员评估了母乳喂养与一岁时哮鸣音之间的相关性。

研究人员分析了来自于加拿大健康婴儿纵向发育(CHILD研究)出生队列的2773名婴儿。照顾者报道了婴儿在3个月、6个月和12个月母乳喂养和哮鸣音发作的情况。母乳喂养被分为全部、部分(补充配方乳或辅食)或无。

总体而言,21%的母亲患有哮喘,46%的儿童接受母乳喂养至少12个月,并且有21%的婴儿出现了哮鸣音。在患有哮喘的母亲中,母乳喂养与婴幼儿哮鸣音之间呈负相关性,且独立于母亲吸烟、教育和其他风险因素(母乳喂养≥12个月相比于<6个月,调整后的比率(aRR)为0.52;95%可信区间为0.35-0.77)。与在6个月没有进行母乳喂养的婴幼儿相比,哮鸣音在全部母乳喂养的婴幼儿减少了62%(aRR为0.38,95%可信区间为0.20-0.71),以及部分母乳喂养添加辅食的婴幼儿减少了37%(aRR为0.63;95%可信区间为0.43-0.93);然而,当补充配方乳时,母乳喂养的保护性不明显(aRR为0.89;95%可信区间为0.61-1.30)。在没有哮喘的母亲,这种相关性均不显著(相互作用P值<0.01)。

由此可见,在哮喘母亲生出的婴儿中,母乳喂养似乎能以剂量依赖的方式保护哮鸣音。

原始出处:


Meghan B. Azad,et al. Breastfeeding, maternal asthma and wheezing in the first year of life: a longitudinal birth cohort study. Eur Respir J. http://erj.ersjournals.com/content/49/5/1602019

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1665022, encodeId=d4a916650224a, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Sun Sep 03 12:53:00 CST 2017, time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215079, encodeId=3dc72150e931, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Sun Jun 25 07:16:20 CST 2017, time=2017-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299556, encodeId=7b0912995569d, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Fri Jun 23 07:53:00 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213583, encodeId=d14b213583cb, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Wed Jun 21 19:08:15 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213553, encodeId=fca92135533b, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Jun 21 17:08:15 CST 2017, time=2017-06-21, status=1, ipAttribution=)]
    2017-06-25 杨利洪

    学习了分享了

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    2017-06-23 villahu
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    2017-06-21 dhzzm

    学习了分享了

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    2017-06-21 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

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