Dermatol Surg:透明质酸填充物可重塑皮肤!

2016-03-29 Seven L MedSci原创

近期发表在Dermatol Surg的研究称,接受透明质酸真皮填充物的患者其表皮层会增加,在随访过程中,胶原纤维也会增加。

近期发表在Dermatol Surg的研究称,接受透明质酸真皮填充物的患者其表皮层会增加,在随访过程中,胶原纤维也会增加。


巴西尼泰罗伊弗洛米嫩塞联邦大学的 Fabiana Braga França Wanick博士和同事在研究者写道:“光老化的脸部填充玻尿酸,临床上得到显著改善,长期随访中,皮肤得到重塑。形态分析表明,使用透明质酸填充物后3个月和9个月时,胶原蛋白增加;9个月时候的弹性纤维也增加。此外,真皮填充透明质酸能维持9个月以上,这个时间是有报道以来最长的时间段之一。”

该研究中Wanick和同事对20名接受了24 mg/mL透明质酸填充双边鼻唇和耳前皱襞的患者,在研究前和填充后随访的3月和9月,对耳前褶皱的皮肤进行活检。

研究者发现,该操作让参与者的表皮层增加了。20名参与者中有16名完成了临床研究,改善情况持续了12个月!此外,在随访的3个月,参与者的胶原纤维增加了34.2% ± 31.5%;第9个月则增加了39.5% ± 39.7%。

Wanick和同事写道:“研究结果表明,透明质酸填充物可显著改善临床情况,引起皮肤重塑!”

原始出处:

Wanick F, et al. Skin Remodeling Using Hyaluronic Acid Filler Injections in Photo-Aged Faces.Dermatol Surg. 2016;doi:10.1097/DSS.0000000000000659.

Hyaluronic acid filler increases epidermal layers, collagen fibers.Healio.March 24, 2016


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=140930, encodeId=fd2e14093052, content=赞一个?, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:01:09 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140929, encodeId=3e5f140929f8, content=透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:00:59 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82522, encodeId=8bf882522a8, content=真的神奇啊,美容利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbd11668261, createdName=小猫cathy, createdTime=Sun Apr 24 16:10:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276706, encodeId=706612e67066e, content=<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94823, encryptionId=ec9e9482383, topicName=透明质酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Thu Mar 31 06:14:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74646, encodeId=19eee464649, content=可以放心打玻尿酸了啊,哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=79191706277, createdName=1de91ba0m10(暂无匿称), createdTime=Wed Mar 30 12:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=)]
    2016-10-06 榄枷檬

    赞一个?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=140930, encodeId=fd2e14093052, content=赞一个?, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:01:09 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140929, encodeId=3e5f140929f8, content=透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:00:59 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82522, encodeId=8bf882522a8, content=真的神奇啊,美容利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbd11668261, createdName=小猫cathy, createdTime=Sun Apr 24 16:10:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276706, encodeId=706612e67066e, content=<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94823, encryptionId=ec9e9482383, topicName=透明质酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Thu Mar 31 06:14:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74646, encodeId=19eee464649, content=可以放心打玻尿酸了啊,哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=79191706277, createdName=1de91ba0m10(暂无匿称), createdTime=Wed Mar 30 12:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=)]
    2016-10-06 榄枷檬

    透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=140930, encodeId=fd2e14093052, content=赞一个?, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:01:09 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140929, encodeId=3e5f140929f8, content=透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:00:59 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82522, encodeId=8bf882522a8, content=真的神奇啊,美容利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbd11668261, createdName=小猫cathy, createdTime=Sun Apr 24 16:10:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276706, encodeId=706612e67066e, content=<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94823, encryptionId=ec9e9482383, topicName=透明质酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Thu Mar 31 06:14:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74646, encodeId=19eee464649, content=可以放心打玻尿酸了啊,哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=79191706277, createdName=1de91ba0m10(暂无匿称), createdTime=Wed Mar 30 12:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=)]
    2016-04-24 小猫cathy

    真的神奇啊,美容利器

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=140930, encodeId=fd2e14093052, content=赞一个?, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:01:09 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140929, encodeId=3e5f140929f8, content=透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:00:59 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82522, encodeId=8bf882522a8, content=真的神奇啊,美容利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbd11668261, createdName=小猫cathy, createdTime=Sun Apr 24 16:10:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276706, encodeId=706612e67066e, content=<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94823, encryptionId=ec9e9482383, topicName=透明质酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Thu Mar 31 06:14:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74646, encodeId=19eee464649, content=可以放心打玻尿酸了啊,哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=79191706277, createdName=1de91ba0m10(暂无匿称), createdTime=Wed Mar 30 12:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=140930, encodeId=fd2e14093052, content=赞一个?, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:01:09 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140929, encodeId=3e5f140929f8, content=透明质酸填充物可重塑皮肤,使表皮层增加,皮肤胶原蛋白含量增加,使皮肤年轻化,达到减龄的效果!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Oct 06 13:00:59 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=82522, encodeId=8bf882522a8, content=真的神奇啊,美容利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbd11668261, createdName=小猫cathy, createdTime=Sun Apr 24 16:10:00 CST 2016, time=2016-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276706, encodeId=706612e67066e, content=<a href='/topic/show?id=ec9e9482383' target=_blank style='color:#2F92EE;'>#透明质酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94823, encryptionId=ec9e9482383, topicName=透明质酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Thu Mar 31 06:14:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74646, encodeId=19eee464649, content=可以放心打玻尿酸了啊,哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=79191706277, createdName=1de91ba0m10(暂无匿称), createdTime=Wed Mar 30 12:00:00 CST 2016, time=2016-03-30, status=1, ipAttribution=)]
    2016-03-30 1de91ba0m10(暂无匿称)

    可以放心打玻尿酸了啊,哈哈

    0

相关资讯

New Scientist:科学家称裸鼹鼠体内神秘物质具有癌症免疫性

据英国新科学家杂志报道,如果与裸鼹鼠的身体大小作为参照对比,人类的寿命将达到600岁。与老鼠体型接近的裸鼹鼠生活在非洲的地下环境,它们的寿命可达到30岁。令科学家感到兴趣的是,这种丑陋的哺乳动物不会患癌症,目前,科学家最新研究揭晓了它们不会患有癌症的秘密,这将对治疗癌症患者提供了重要线索。 科学家最新研究揭晓了裸鼹鼠癌症免疫性的秘密,体内高分子质量透明质酸(HMM-HA)可阻止肿瘤细胞生长 美

JACC:尿透明质酸或能更早预测心脏手术相关急性肾损伤

心脏手术相关急性肾损伤(CSA-AKIA)是体外循环下行心脏手术患者的一个常见且复杂的临床问题,也是心脏手术后伤残和死亡的重要预测因子。 根据血清肌酐水平和/或尿量改变等现行共识标准,CSA-AKI只有在术后24-48小时才能被诊断。尽管CSA-AKI治疗措施有限,但尽早预防进一步损害和及时预测对改善预后至关重要。 虽然研究不断发现新的生物标志物(如尿白介素-18,尿NGAL或尿K

JACC:尿透明质酸是心脏手术相关急性肾损伤早期预测因子

心脏手术相关急性肾损伤(Cardiac surgery-associated acute kidney injury,CSA-AKIA)是体外循环下行心脏手术患者的一个常见且复杂的临床问题,也是心脏手术后伤残和死亡的重要预测因子。根据血清肌酐水平和/或尿量改变等现行共识标准,CSA-AKI只有在术后24-48小时才能被诊断。尽管CSA-AKI治疗措施有限,但尽早预防进一步损害和及时预测对改善预后至

基于透明质酸的方法或改善体外受精的成功率

近日,来自英国利兹大学的科学家通过研究调查了,是否在润肤霜和护肤霜中发现的分子可以有效改善体外受精的成功率;目前研究人员正在进行临床试验,来调查这种在美容产品中存在的名为透明质酸的分子是否可以被重新设计用以维持皮肤的弹性,同时保持头发和关节含水,帮助精子仅仅吸附于卵细胞上。 这种透明质酸的方法仅依赖于成熟和具有生殖能力的精子,其会紧紧吸附于卵细胞上,研究者David Miller表示,我们开

CHEST:COPD的加重与透明质酸的炎性降解相关

慢性阻塞性肺病(COPD)的特征是慢性气道炎症及重塑,与细胞外基质(ECM)的严重变形。透明质酸(HA)是一种丰富的细胞外基质分子,在肺中具有不同的生物功能,这取决于其分子量(MW)。高MW的HA具有抗炎和免疫抑制作用,而MW的HA可促发炎症。在这项研究中,研究人员调查了是否COPD急性加重期(AECOPDs)(影响患者的生活和生存生存质量)和BAL中的HA改变有关,研究人员使用了COPD稳定期患