Graefes Arch Clin Exp Ophthalmol:人体晶状体对环境辐射的光毒性综述-重新审视紫外线诱发白内障的发病机制

2019-06-28 MedSci 网络

伊朗大不里士医科大学眼科研究中心的Kamari F等人在 Graefes Arch Clin Exp Ophthalmol杂志上发表了一篇综述文章,对人体晶状体对环境辐射的光毒性进行了综述,重新审视了紫外线诱发白内障的发病机制。

伊朗大不里士医科大学眼科研究中心的Kamari F等人在 Graefes Arch Clin Exp Ophthalmol杂志上发表了一篇综述文章,对人体晶状体对环境辐射的光毒性进行了综述,重新审视了紫外线诱发白内障的发病机制。

白内障病理学的严重程度很重要,因为它是全世界失明的主要原因。此外,这一问题的突出性随着当前人口老龄化而加剧。在发展中国家,这种疾病的负担比发达国家更为明显。关于这一问题,在对紫外线(UV)辐射诱发的白内障的发病机理进行分类并解释可能的细胞和亚细胞途径方面存在差距。

在这篇综述中,他们的目的是重新审视紫外线辐射对分类所涉细胞通路的白内障的影响。这可能有助于更好的药物治疗替代品及其广泛的可用性。此外,他们概述了用防紫外线作为屏蔽剂的保护性作用。同时,作者也指出,需要进一步的研究来探索晶状体中紫外线辐射诱发的病理学的新的治疗方式。

原文出处:

Kamari, F., et al., Phototoxicity of environmental radiations in human lens: revisiting the pathogenesis of UV-induced cataract. Graefes Arch Clin Exp Ophthalmol, 2019.

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    2019-06-30 jiyangfei
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    2019-06-29 百草

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