J Am Acad Dermatol:甲下黑色素瘤与甲下鳞状细胞癌的碰撞

2017-10-31 MedSci MedSci原创

背景:甲下鳞状细胞癌(Subungual squamous cell carcinoma,SSCC)和甲下黑色素瘤(subungual melanoma,SUM)都是罕见的恶性肿瘤,其临床预后较差。相对于少见的SSCC和SUM,SSCC伴随SUM(SSCC-SUM)更为罕见,但是临床上依然有一些SSCC和SUM同时出现(SSCC-SUM)的病例报告。目的:研究人员试图记录SSCC-SUM病例系列的

背景:甲下鳞状细胞癌(Subungual squamous cell carcinoma,SSCC)和甲下黑色素瘤(subungual melanoma,SUM)都是罕见的恶性肿瘤,其临床预后较差。相对于少见的SSCC和SUM,SSCC伴随SUM(SSCC-SUM)更为罕见,但是临床上依然有一些SSCC和SUM同时出现(SSCC-SUM)的病例报告。目的:研究人员试图记录SSCC-SUM病例系列的临床、皮肤镜和组织学特征,并描述与SSCC和SUM相比,SSCC-SUM发病的相对频率。方法:这是一项回顾性研究。研究人员回顾性分析了2012年-2015年间所有行指甲皮肤病理检查的数据,以找出所有的SSCC、SUM和SSCC-SUM患者。研究人员从SSCC-SUM患者的电子医疗记录获得他们的临床特征。所有组织标本都被3名皮肤病理学家回顾与分析。结果:研究人员共对456例患者进行了回顾性分析。其中,78例患者被诊断为SSCC(17%,n =78/456),63例患者被诊断为SUM(14%,n =63/456),9例诊断为SSCC-SUM。在诊断为SSCC和SUM的患者中,SSCC-SUM患者分

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    2018-01-10 sunylz
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    2017-12-14 lishizhe
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    2017-11-04 wxl882001

    学习一下

    0

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