Dev Med Child Neurol:探究脑瘫患儿疼痛随时间变化的相关因素

2017-05-11 MedSci MedSci原创

本研究旨在识别脑性瘫痪(CP)患儿疼痛随时间变化的相关因素。由医生在两个时间点以及患儿照顾者相关的健康效用指数3 (HUI3)得分对患儿的疼痛进行评估。研究共纳入了179个门诊的148名患儿(83%响应;104名男性,44名女性,平均年龄为8.8年,范围3-16年),脑瘫粗大运动功能分级系统(GMFCS)的水平均纳入。55名患儿的照顾者报道的HUI3疼痛有所改变。逐步多元线性回归保留HUI3疼痛得

本研究旨在识别脑性瘫痪(CP)患儿疼痛随时间变化的相关因素。

由医生在两个时间点以及患儿照顾者相关的健康效用指数3 (HUI3)得分对患儿的疼痛进行评估。

研究共纳入了179个门诊的148名患儿(83%响应;104名男性,44名女性,平均年龄为8.8年,范围3-16年),脑瘫粗大运动功能分级系统(GMFCS)的水平均纳入。55名患儿的照顾者报道的HUI3疼痛有所改变。逐步多元线性回归保留HUI3疼痛得分在第一次随访及GMFCS水平(F[2,144] =23.40, R2 =0.35; p<0.001)作为有疼痛状态改变有关的变量(首次随访HUI3疼痛: β=0.61, p<0.001; GMFCS level: β=-0.17, p<0.015)。在第1次随访时的HUI3疼痛和GMFCS水平之间的相关性具有统计学意义(β= -0.15,P<0.036)。疼痛的病因和疼痛轨迹之间具有关联(F[3,144] =5.39, p=0.002)。Post-hoc测试显示,与无疼痛组相比,肌肉骨骼疼痛改善最大(P = 0.006)

初始疼痛更重及更高的粗大运动功能分级系统的脑瘫患儿随访期间疼痛情况更轻表明患儿疼痛情况随时间的推移有所改善。

原始出处:

Christensen R, MacIntosh A, et al., Change in pain status in children with cerebral palsy. Dev Med Child Neurol. 2017 Apr;59(4):374-379. doi: 10.1111/dmcn.13328. Epub 2016 Nov 15.

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    2017-07-03 yinhl1978
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    2017-09-02 docwu2019
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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri May 12 10:20:40 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2018-03-11 fzwish20000
  5. 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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri May 12 10:20:40 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-15 jacob9231

    学习了,谢谢分享

    0

  6. 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  8. 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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri May 12 10:20:40 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-12 天涯183

    非常好的文章,学习了,很受益

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri May 12 10:20:40 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-12 Hero223

    值得学习,学习分享

    0

  10. 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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri May 12 10:20:40 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-12 明月清辉

    谢谢分享,学习了

    0

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