Cell Metabolism:想减肥?低脂饮食效果更好

2015-08-14 MedSci MedSci原创

说到减肥,大家都想知道哪种饮食才是最好和最有效的饮食,既能够有效减少机体脂肪,又不会为机体带来副作用。研究人员通过比较低脂饮食和低碳水化合物饮食,他们发现,低脂饮食更能有效减少体内脂肪。研究人员进行了一项规模虽小但十分缜密的试验,在病房内选取了19名肥胖患者,观察他们两周内的体重变化情况,并将研究结果发表在Cell Metabolism杂志上。Kevin Hall是NIDDK的代谢学研究人员,他认

说到减肥,大家都想知道哪种饮食才是最好和最有效的饮食,既能够有效减少机体脂肪,又不会为机体带来副作用。研究人员通过比较低脂饮食和低碳水化合物饮食,他们发现,低脂饮食更能有效减少体内脂肪。


研究人员进行了一项规模虽小但十分缜密的试验,在病房内选取了19名肥胖患者,观察他们两周内的体重变化情况,并将研究结果发表在Cell Metabolism杂志上。

Kevin Hall是NIDDK的代谢学研究人员,他认为很多人都有强烈的减肥信念,但是相关调查数据并不充分且真实。他强烈建议通过严格限制饮食中碳水化合物的含量,以探究这种干预措施是否对减轻体重有意义。但是,想做到这一点并不容易,因为即便他们向参与者健康宣教十分准确,参与者也很难坚持该膳食计划,并且他们主诉的饮食情况的真实性还有待考证。因此,研究者将参与者聚集到病房,时刻监测和控制参与者的饮食成分和含量。

实验分两个阶段进行:第一阶段,限制30%的参与者饮食中的碳水化合物含量,脂肪摄入量不变;第二阶段,限制另外30%参与者饮食中脂肪摄入量的含量,碳水化合物摄入量不变。通过测量参与者每日脂肪摄入量和脂肪氧化率的差异,由此计算出参与者机体脂肪的减少量。

通过使用数学模型,Hall认为低碳水化合物饮食会导致机体脂肪消耗增多,而低脂饮食会导致全身脂肪减少最多。最后, Hall的假设被证实。

研究人员建议,通过数学模型可知,机体脂肪减少之后,机体便会改变膳食结构或含量以平衡热量的摄入量和消耗量。

但是,实验的缺点在于参与者过少,且对自由的民众而言,将他们困在病房内是不切实际的,并且也不能通过严格控制饮食的摄入成分来减少体内脂肪,因为普通民众很难严格计算三大供能物质的含量。因此在实际生活中,到底是否应该坚持低脂饮食还要通过更进一步的研究才可得以证实。希望可以尽早获得有效结果,以便改善患者的生活质量和健康状况。

原始出处:
Low-fat diet more effective than low-carb diet for losing body fat,Kevin D. Hall et al., Cell Metabolism, doi: http://dx.doi.org/10.1016/j.cmet.2015.07.021, published online 13 August 2015, abstract

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    2015-10-16 guojianrong
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    2016-03-27 智智灵药
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    2016-02-05 一闲
  4. [GetPortalCommentsPageByObjectIdResponse(id=1887453, encodeId=6e0c188e453b4, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Oct 16 08:50:00 CST 2015, time=2015-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959440, encodeId=0585195944063, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Mar 27 17:50:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895820, encodeId=67ed1895820c7, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Feb 05 06:50:00 CST 2016, time=2016-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869185, encodeId=b5a61869185b4, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Fri Jul 29 08:50:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390628, encodeId=1aa013906286e, content=<a href='/topic/show?id=4fb326339ad' target=_blank style='color:#2F92EE;'>#低脂饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26339, encryptionId=4fb326339ad, topicName=低脂饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b78f2500065, createdName=12498761m56暂无昵称, createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577152, encodeId=1d6315e71525a, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597938, encodeId=215f159e9386f, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35688, encodeId=959635688e4, content=这视角!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Sun Aug 16 11:57:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35679, encodeId=21dd356e9de, content=这不是废话嘛, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Aug 16 11:22:00 CST 2015, time=2015-08-16, status=1, ipAttribution=)]
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1887453, encodeId=6e0c188e453b4, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Oct 16 08:50:00 CST 2015, time=2015-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959440, encodeId=0585195944063, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Mar 27 17:50:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895820, encodeId=67ed1895820c7, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Feb 05 06:50:00 CST 2016, time=2016-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869185, encodeId=b5a61869185b4, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Fri Jul 29 08:50:00 CST 2016, time=2016-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390628, encodeId=1aa013906286e, content=<a href='/topic/show?id=4fb326339ad' target=_blank style='color:#2F92EE;'>#低脂饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26339, encryptionId=4fb326339ad, topicName=低脂饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b78f2500065, createdName=12498761m56暂无昵称, createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577152, encodeId=1d6315e71525a, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597938, encodeId=215f159e9386f, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Sun Aug 16 14:50:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35688, encodeId=959635688e4, content=这视角!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b531630898, createdName=pine007, createdTime=Sun Aug 16 11:57:00 CST 2015, time=2015-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35679, encodeId=21dd356e9de, content=这不是废话嘛, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Aug 16 11:22:00 CST 2015, time=2015-08-16, status=1, ipAttribution=)]
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    2015-08-16 闆锋旦
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    2015-08-16 pine007

    这视角!!

    0

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    2015-08-16 stupidox

    这不是废话嘛

    0

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