Allergol Int:在健康和哮喘患者中,血清骨膜蛋白与身体质量指数和过敏性鼻炎相关

2017-12-22 AlexYang MedSci原创

许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素。然而,这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究,这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰。最近,有研究人员确定了在健康受试者中,与血清骨膜蛋白水平相关的因素。研究人员同样在哮喘患者中评估了一些因素,从而认知它们在哮喘中的作用。研究测量了230健康受试者的血清骨膜蛋白水平。感兴趣的临床因素包括了身体质量指数(

许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素。然而,这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究,这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰。最近,有研究人员确定了在健康受试者中,与血清骨膜蛋白水平相关的因素。研究人员同样在哮喘患者中评估了一些因素,从而认知它们在哮喘中的作用。

研究测量了230健康受试者的血清骨膜蛋白水平。感兴趣的临床因素包括了身体质量指数(BMI)和过敏性鼻炎(AR)。另外,研究人员还确定了是否这些因素在206名哮喘受试者中与血清骨膜蛋白相关,还评估了几种肥胖相关的参数,比如腹部脂肪分布和脂肪细胞因子水平。研究发现,抽烟、血液嗜酸性粒细胞数目、总免疫球蛋白E和AR的存在在健康群体中与血清骨膜蛋白存在相关关系。在健康和哮喘受试者中,BMI与血清骨膜蛋白具有负相关关系,而在哮喘患者中具有与AR正相关关系的趋势。在哮喘病人中,皮下的和腹部的脂肪与血清骨膜蛋白没有关联。另外,血清骨膜与血清中脂联素水平显著相关,但与瘦素无关。最后,研究人员指出,他们的结果鉴定了与血清骨膜蛋白水平相关的因素,这将在临床实践中解释血清骨膜蛋白水平中具有帮助。

原始出处:


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  4. 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    2018-01-15 zzl0611_64089391

    学到了新知识.谢谢分享

    0

  5. 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    2018-01-15 zzl0611_64089391

    学习了

    0

  6. 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    2017-12-24 沙漠浪人

    血清骨膜与血清中脂联素水平显著相关.但与瘦素无关

    0

  7. 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createdName=zzl0611_64089391, createdTime=Mon Jan 15 21:31:08 CST 2018, time=2018-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=278825, encodeId=73d82e882526, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f6352227688, createdName=zzl0611_64089391, createdTime=Mon Jan 15 21:30:41 CST 2018, time=2018-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272164, encodeId=6a4a2e21642e, content=血清骨膜与血清中脂联素水平显著相关.但与瘦素无关, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sun Dec 24 16:22:16 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329052, encodeId=027113290520a, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sun Dec 24 11:55:00 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271697, encodeId=92ab2e16975d, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Sat Dec 23 05:36:11 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271681, encodeId=10a92e1681ba, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Dec 23 00:29:23 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271654, encodeId=2bd62e165406, content=许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素.然而.这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究.这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰., 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    2017-12-24 膀胱癌
  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Sat Dec 23 05:36:11 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271681, encodeId=10a92e1681ba, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Dec 23 00:29:23 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271654, encodeId=2bd62e165406, content=许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素.然而.这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究.这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 22 23:47:48 CST 2017, time=2017-12-22, status=1, ipAttribution=)]
    2017-12-23 changjiu

    学习一下谢谢

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Sat Dec 23 05:36:11 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271681, encodeId=10a92e1681ba, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Dec 23 00:29:23 CST 2017, time=2017-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271654, encodeId=2bd62e165406, content=许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素.然而.这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究.这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 22 23:47:48 CST 2017, time=2017-12-22, status=1, ipAttribution=)]
    2017-12-23 飛歌

    学习了很有用

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 22 23:47:48 CST 2017, time=2017-12-22, status=1, ipAttribution=)]
    2017-12-22 有备才能无患

    许多研究在哮喘患者中尝试鉴定了与血清骨膜蛋白水平相关的因素.然而.这些研究的结果主要基于对具有高嗜酸性粒细胞数目患者的研究.这也许会对与血清骨膜蛋白水平相关的其他因素的鉴定造成干扰.

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