JAHA:妊娠高血压疾病和妊娠前高血压的女性在分娩后心衰风险

2021-08-26 MedSci原创 MedSci原创

患有HDP和孕前高血压的妇女在分娩后5年内有较高的HF风险(伴有先兆子痫的患者最高)。无论是否有孕前高血压,伴有HDP的NHB女性发生HF风险高于NHW女性。

妊娠期高血压疾病(HDP)和孕前高血压与母亲的发病率和死亡率增加有关。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在调查HDP与孕前高血压与孕妇分娩后1年和5年心力衰竭(HF)之间的关系,并评估人种/民族差异。

研究人员在南卡罗来纳州进行了一项回顾性队列研究(2004年-2016年),纳入了425649名12至49岁的活产单胎妇女(58.9%非西班牙裔白人[NHW],31.5%非西班牙裔黑人[NHB],9.6%西班牙裔人)。HF事件由医院/急诊科就诊和死亡证明数据来确定。孕前高血压和HDP(先兆子痫、子痫或妊娠高血压)是基于住院/急诊科和出生证明数据(即HDP的妊娠高血压)。

425649名孕妇患有不伴有HDP的孕前高血压(单独的孕前高血压;0.4%)、单独的HDP(15.7%)、伴有HDP的孕前高血压(两种情况;2.2%),或两者都没有(81.7%)。NHB中每1000人每年HF事件发生率高于患有HDP的NHW女性(HDP:2.28 vs. 0.96;两种情况:分别为4.30和1.22)。调整后,与两者都没有的妇女相比,妊娠前高血压(HR为2.55,95%CI为1.31-4.95)、HDP(HR为4.20,95%CI为3.66-4.81)和两者都有(HR为5.25,95%CI为4.24-6.50)的妇女在分娩后5年内发生HF的风险增加。

由此可见,患有HDP和孕前高血压的妇女在分娩后5年内有较高的HF风险(伴有先兆子痫的患者最高)。无论是否有孕前高血压,伴有HDP的NHB女性发生HF风险高于NHW女性。

原始出处:

Angela M. Malek.et al.Incident Heart Failure Within the First and Fifth Year after Delivery Among Women With Hypertensive Disorders of Pregnancy and Prepregnancy Hypertension in a Diverse Population.JAHA.2021.https://www.ahajournals.org/doi/10.1161/JAHA.121.021616

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    2021-09-19 鸿毳沉舟

    学学习习。很好。

    0

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    2021-08-28 zhaohui6731
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    2021-08-28 linlin2312
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1946751, encodeId=6e4b1946e512d, content=<a href='/topic/show?id=8a0844838ca' target=_blank style='color:#2F92EE;'>#妊娠前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44838, encryptionId=8a0844838ca, topicName=妊娠前)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Fri Oct 29 18:46:25 CST 2021, time=2021-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052976, encodeId=4d3510529e6c1, content=学学习习。很好。, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7995605070, createdName=鸿毳沉舟, createdTime=Sun Sep 19 10:02:14 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268614, encodeId=5ef0126861415, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275221, encodeId=c5c812e5221c8, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389483, encodeId=fc31138948307, content=<a href='/topic/show?id=8425519625e' target=_blank style='color:#2F92EE;'>#心衰风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51962, encryptionId=8425519625e, topicName=心衰风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492011, encodeId=462c14920116a, content=<a href='/topic/show?id=4ff54492941' target=_blank style='color:#2F92EE;'>#妊娠高血压疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44929, encryptionId=4ff54492941, topicName=妊娠高血压疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb88907518, createdName=zhangjiqing, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031119, encodeId=626d103111971, content=妊娠高血压这一类妊娠疾病,需要加强关注,甚至包括妊娠心肌病, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=IVF密密, createdTime=Thu Aug 26 17:46:25 CST 2021, time=2021-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1011718, encodeId=d42d1011e18ef, content=今天又比昨天更进步了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoSS4DfecudGejMHxtB9K7cDNY3megEnCVWSGG7HJia7AgxYpFGfYNTIkFgfo8WGwBAGYC56DicF3UA/132, createdBy=baca2550536, createdName=放晴sunny, createdTime=Thu Aug 26 15:14:07 CST 2021, time=2021-08-26, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1946751, encodeId=6e4b1946e512d, content=<a href='/topic/show?id=8a0844838ca' target=_blank style='color:#2F92EE;'>#妊娠前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44838, encryptionId=8a0844838ca, topicName=妊娠前)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Fri Oct 29 18:46:25 CST 2021, time=2021-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052976, encodeId=4d3510529e6c1, content=学学习习。很好。, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7995605070, createdName=鸿毳沉舟, createdTime=Sun Sep 19 10:02:14 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268614, encodeId=5ef0126861415, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275221, encodeId=c5c812e5221c8, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389483, encodeId=fc31138948307, content=<a href='/topic/show?id=8425519625e' target=_blank style='color:#2F92EE;'>#心衰风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51962, encryptionId=8425519625e, topicName=心衰风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492011, encodeId=462c14920116a, content=<a href='/topic/show?id=4ff54492941' target=_blank style='color:#2F92EE;'>#妊娠高血压疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44929, encryptionId=4ff54492941, topicName=妊娠高血压疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb88907518, createdName=zhangjiqing, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031119, encodeId=626d103111971, content=妊娠高血压这一类妊娠疾病,需要加强关注,甚至包括妊娠心肌病, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=IVF密密, createdTime=Thu Aug 26 17:46:25 CST 2021, time=2021-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1011718, encodeId=d42d1011e18ef, content=今天又比昨天更进步了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoSS4DfecudGejMHxtB9K7cDNY3megEnCVWSGG7HJia7AgxYpFGfYNTIkFgfo8WGwBAGYC56DicF3UA/132, createdBy=baca2550536, createdName=放晴sunny, createdTime=Thu Aug 26 15:14:07 CST 2021, time=2021-08-26, status=1, ipAttribution=)]
    2021-08-26 IVF密密

    妊娠高血压这一类妊娠疾病,需要加强关注,甚至包括妊娠心肌病

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1946751, encodeId=6e4b1946e512d, content=<a href='/topic/show?id=8a0844838ca' target=_blank style='color:#2F92EE;'>#妊娠前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44838, encryptionId=8a0844838ca, topicName=妊娠前)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=38232500109, createdName=1249898am15暂无昵称, createdTime=Fri Oct 29 18:46:25 CST 2021, time=2021-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1052976, encodeId=4d3510529e6c1, content=学学习习。很好。, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7995605070, createdName=鸿毳沉舟, createdTime=Sun Sep 19 10:02:14 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268614, encodeId=5ef0126861415, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275221, encodeId=c5c812e5221c8, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389483, encodeId=fc31138948307, content=<a href='/topic/show?id=8425519625e' target=_blank style='color:#2F92EE;'>#心衰风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51962, encryptionId=8425519625e, topicName=心衰风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1492011, encodeId=462c14920116a, content=<a href='/topic/show?id=4ff54492941' target=_blank style='color:#2F92EE;'>#妊娠高血压疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44929, encryptionId=4ff54492941, topicName=妊娠高血压疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb88907518, createdName=zhangjiqing, createdTime=Sat Aug 28 05:46:25 CST 2021, time=2021-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031119, encodeId=626d103111971, content=妊娠高血压这一类妊娠疾病,需要加强关注,甚至包括妊娠心肌病, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=IVF密密, createdTime=Thu Aug 26 17:46:25 CST 2021, time=2021-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1011718, encodeId=d42d1011e18ef, content=今天又比昨天更进步了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoSS4DfecudGejMHxtB9K7cDNY3megEnCVWSGG7HJia7AgxYpFGfYNTIkFgfo8WGwBAGYC56DicF3UA/132, createdBy=baca2550536, createdName=放晴sunny, createdTime=Thu Aug 26 15:14:07 CST 2021, time=2021-08-26, status=1, ipAttribution=)]
    2021-08-26 放晴sunny

    今天又比昨天更进步了

    0

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