Fertility Sterility:备孕期及孕早期,请远离咖啡因

2016-03-25 Seven L 译 MedSci原创

发表在Fertility and Sterility的研究称,准爸爸和准妈妈在受孕那周平均每天摄入≥2份喊咖啡因的饮料,会增加流产风险。不过,如果在受孕前和早孕期每天摄入多种维生素,则可以降低流产风险。研究者对344对单胎妊娠夫妇进行了研究,探究了从受孕前一周到妊娠第7周,生活因素如吸烟、摄入含咖啡因的饮料和多种维生素对妊娠的影响。研究数据显示,流产率为28%(98例),如果怀孕前女性年龄≥35岁

发表在Fertility and Sterility的研究称,准爸爸和准妈妈在受孕那周平均每天摄入≥2份含咖啡因的饮料,会增加流产风险。不过,如果在受孕前和早孕期每天摄入多种维生素,则可以降低流产风险。

研究者对344对单胎妊娠夫妇进行了研究,探究了从受孕前一周到妊娠第7周,生活因素如吸烟、摄入含咖啡因的饮料和多种维生素对妊娠的影响。

研究数据显示,流产率为28%(98例),如果怀孕前女性年龄≥35岁,流产风险是正常女性的近2倍(HR=1.96)。无论男女,每日摄入含咖啡因的饮料≥2份,也会增加流产风险(女性 HR=1.74,男性 HR=1.73)。

先前有研究表明,孕早期摄入咖啡因会增加流产风险,但是在本研究中无法得出孕早期摄入咖啡因和流产的关系,因为两者之间的混杂因素太多。而受孕前摄入咖啡因导致的更高的流产风险,则可能是咖啡因的直接作用。

最后研究者还发现,每天摄入多种维生素的女性的流产风险可降低。怀孕前就开始摄入可降低55%的风险(HR=0.45),孕早期摄入则可以降低79%的风险(HR=0.21)。

此外其他研究也表明,维生素B6和叶酸可降低流产风险。指南建议育龄期女性从准备怀孕时,就要开始摄入叶酸补充剂,以降低胎儿神经管畸形的风险。

原始出处:

Germaine M. Buck Louis et al. Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception: The LIFE Study, Fertility and Sterility (2016).

Couples' pre-pregnancy caffeine consumption linked to miscarriage risk.MedicalXpress.March 24, 2016


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    2016-04-25 1dea6088m20(暂无匿称)

    叶酸400微克每日于孕前几亇月就应给予预防新生儿神经管畸形维生素B6饮食提供

    0

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    2016-03-27 zhouqu_8