Stroke:老年患者脑静脉血栓形成剖析!

2017-12-06 xing.T MedSci原创

由此可见,老年患者中CVT的性别比例是均匀分布的,可能是由于激素效应消失所致。恶性肿瘤应被视为一个老年CVT患者潜在的不利因素。

脑静脉血栓形成(CVT)在老年患者中较为罕见。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在调查老年和年轻患者的临床特征和结局是否有所不同。

研究人员从多中心观察登记中心获取1987年至2016年期间连续住院的成年CVT患者数据,并比较了老年(年龄分布处于上四分位数)和年轻(年龄处于下3个四分位数的患者)受试者人口统计学、临床表现和结局之间的差异。

研究人员共获取了843例CVT患者的资料。年龄中位数为43岁(四分位距为30-55岁)。老年患者(≥55岁;n=222)相比于年轻患者女性比例较少(48% vs. 71%;P<0.001),并且报告头痛的患者比例也较少(63% vs. 87%;P<0.001)。癌症在老年患者中更为常见(24% vs. 9%,P<0.001),尤其是恶性实体肿瘤(19% vs. 5%,P<0.001)。老年患者的随访预后较差(改良的Rankin量表得分为3-6;调整后的比值比为2.68;95%可信区间为1.78-4.03;死亡率,调整后的比值比为2.13;95%可信区间为1.09-4.19)。

由此可见,老年患者中CVT的性别比例是均匀分布的,可能是由于激素效应消失所致。恶性肿瘤应被视为一个老年CVT患者潜在的不利因素。

原始出处:

Susanna M. Zuurbier,et al. Cerebral Venous Thrombosis in Older Patients.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.019483

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    2018-09-14 xue8602
  2. [GetPortalCommentsPageByObjectIdResponse(id=1955329, encodeId=57051955329af, content=<a href='/topic/show?id=0aeb991e44c' target=_blank style='color:#2F92EE;'>#静脉血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99174, encryptionId=0aeb991e44c, topicName=静脉血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d139492, createdName=xue8602, createdTime=Fri Sep 14 08:47:00 CST 2018, time=2018-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=279786, encodeId=774b2e97867c, content=学习了!谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdgSW0vVibEHQRlKXLlvMibvcHmy5ibwM7Luib2am6ywX6FqBrXibF8k7JVEzriaOSghltmYz1nomRd6TgSp2Yj9xHGAY/0, createdBy=9b2f2045808, createdName=haige, createdTime=Thu Jan 18 19:50:20 CST 2018, time=2018-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1697593, encodeId=1bef169e59334, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Thu Feb 15 14:47:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268367, encodeId=e85026836eb3, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 10 13:01:06 CST 2017, time=2017-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267889, encodeId=be3526e8896f, content=老年患者中CVT的性别比例是均匀分布的.可能是由于激素效应消失所致.恶性肿瘤应被视为一个老年CVT患者潜在的不利因素., beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Fri Dec 08 21:17:04 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483260, encodeId=d71d14832601a, content=<a href='/topic/show?id=c82e991e71b' target=_blank style='color:#2F92EE;'>#静脉血栓形成#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99177, encryptionId=c82e991e71b, topicName=静脉血栓形成)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1d387907505, createdName=ms5187542471278033, createdTime=Fri Dec 08 03:47:00 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267279, encodeId=685626e279f4, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Dec 06 14:13:39 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267271, encodeId=9fa526e27109, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:03:24 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2018-01-18 haige

    学习了!谢谢!

    0

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    2018-02-15 fusion
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    2017-12-10 131****1460

    学习了受益匪浅

    0

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    2017-12-08 沙漠浪人

    老年患者中CVT的性别比例是均匀分布的.可能是由于激素效应消失所致.恶性肿瘤应被视为一个老年CVT患者潜在的不利因素.

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