Dent Mater J:采用间充质干细胞和生物材料实施的牙周再生疗法:一项临床前研究的文献回顾

2019-09-15 lishiting MedSci原创

这篇系统性文献回顾的目的是为了分析使用间充质干细胞(MSC)和生物材料在临床前动物模型和人上实施牙周再生疗法的使用情况。

这篇系统性文献回顾的目的是为了分析使用间充质干细胞(MSC)和生物材料在临床前动物模型和人上实施牙周再生疗法的使用情况。研究通过电子数据库辅以额外的手动检索在权威杂志内寻找相关报道。文献的搜索策略按照系统评价和元分析(PRISMA)指南的首选报告项目执行。涉及以下标准:MSC、生物材料、体内研究、含组织学和X线影像分析以及英文文章。个别文献实施偏倚性风险评估。结果显示,研究共纳入了50篇文献并进行了系统性的回顾分析。结果表明,MSC和支架材料能够为牙周再生提供更好的效果,并且不存在干预的不良影响。然而,还需要更多研究来验证MSC和生物材料之间的适合行,需要鉴定新形成的牙骨质类型以及再生牙周膜纤维的构成。原始出处:Portron S, Soueidan A, et al. Periodontal regenerative medicine using mesenchymal stem cells and biomaterials: A systematic review of pre-clinical studies. Dent Mater J. 2019 Sep 11. doi: 10

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    2019-10-09 流浪的门牙

    插眼

    0

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    2019-09-18 独孤立克

    干细胞是热点,但是进入临床仍然需要时间和临床疗效验证哦

    0

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