N Engl J Med:心电图后皮肤上留下圆圈,老下不去是咋回事?

2017-12-12 卢芳 中国循环杂志

一位53岁的男士,有银屑病史20多年,近日由于皮肤瘙痒和银屑病皮肤损害加剧而就诊。


一位53岁的男士,有银屑病史20多年,近日由于皮肤瘙痒和银屑病皮肤损害加剧而就诊。
 
患者在就诊前3周曾做过心电图,而一周前,放置电极的位置就出现了新皮损。
 
此外,患者躯干、手臂和腿部以及头皮上也可见清晰可见的、大小不一的红色有银色鳞片的斑块。
 
这位患者之前用卡泊三烯和倍他米松治疗不能完全控制症状,之后又因富马酸和氨甲喋呤的不良反应而停药。

此外,药物、感染、局部刺激和心理压力等均能使这种慢性炎症性疾病复发。
 
Koebner现象,也被称为同形反应或同构反应,是指外观正常的皮肤在刮伤、抓伤、针刺、注射后,在该部位发生银屑病皮损。

这种现象在其他皮肤病如白癜风、扁平苔藓等也可见。
 
随后患者在接受了阿达木单抗治疗后,见效迅速,所有皮损愈合。
 
原始出处:

Enrico Streit, Lena E. Vogelgsang. ECG-Induced Koebner Phenomenon. N Engl J Med, 2017, 377: 218.

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    2018-03-10 haouestc
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    2018-06-15 spoonycyy
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1785505, encodeId=95321e85505ad, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Mar 10 12:16:00 CST 2018, time=2018-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081424, encodeId=39f72081424bd, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Jun 15 03:16:00 CST 2018, time=2018-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608342, encodeId=2bdb16083429c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 14 10:16:00 CST 2017, time=2017-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268924, encodeId=226d268924bc, content=好自己好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Tue Dec 12 21:51:16 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268917, encodeId=917c26891ea8, content=特殊病例.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Dec 12 21:10:26 CST 2017, time=2017-12-12, status=1, ipAttribution=)]
    2017-12-12 thlabcde

    好自己好资料学习了!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1785505, encodeId=95321e85505ad, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Mar 10 12:16:00 CST 2018, time=2018-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081424, encodeId=39f72081424bd, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri Jun 15 03:16:00 CST 2018, time=2018-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608342, encodeId=2bdb16083429c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Dec 14 10:16:00 CST 2017, time=2017-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268924, encodeId=226d268924bc, content=好自己好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Tue Dec 12 21:51:16 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268917, encodeId=917c26891ea8, content=特殊病例.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Dec 12 21:10:26 CST 2017, time=2017-12-12, status=1, ipAttribution=)]
    2017-12-12 1e0f8808m18(暂无匿称)

    特殊病例.学习了.

    0

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