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Eur Heart J：生物可吸收支架植入后晚期血栓事件分析！

2017-04-24 xing.T MedSci原创

BVSEES晚期血栓事件
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与EES治疗相比，使用可吸收BVS治疗与较高的DT发生率和更高的TLE风险趋势相关。1.4%的患者发生了VLDT，这些事件多数发生在没有接受DAPT的情况下。

近日，心血管领域权威杂志Eur Heart J上发表了一篇研究文章，研究人员旨在比较经皮冠状动脉介入治疗后生物可吸收血管支架（BVS）和依维莫司洗脱支架（EES）的长期安全性和疗效。

研究人员对比较采用BVS与EES治疗并至少随访24个月的随机临床试验进行系统评价和荟萃分析。经由纳普–哈同法调整后的随机效应模型被用来计算比值比（OR）和95%可信区间（CI）。感兴趣的主要安全性结局为确定/可能的支架内血栓形成（DT）的风险。感兴趣的主要疗效终点为靶病变衰竭（TLF）的风险。

研究人员纳入了5个随机临床试验（n=1730）。采用可吸收BVS治疗的患者相比于EES治疗的患者有较高的发生明确/可能的DT风险（OR为2.93，95%可信区间为1.37-6.26，P=0.01）。13例患者发生极晚期DT（VLDT）[吸收BVS治疗组为12/996（1.4%，95%可信区间为0.08-2.5） vs. EES治疗组为1/701（0.5%，95%可信区间为0.2-1.6）；比值比为3.04；95%可信区间为1.2-7.68，P=0.03]，BVS治疗组发生VLDT的92%患者未接受双联抗血小板治疗（DAPT）。在吸收BVS治疗组患者发生TLE风险有更高的趋势（OR为1.48，95%可信区间为0.90-2.42，P=0.09），主要是由高风险的靶血管心肌梗死和缺血驱动的靶病变血运重建所驱动，心源性死亡风险差异无统计学意义。

与EES治疗相比，使用可吸收BVS治疗与较高的DT发生率和更高的TLE风险趋势相关。1.4%的患者发生了VLDT，这些事件多数发生在没有接受DAPT的情况下。

原始出处：

Carlos Collet ,et al. Late thrombotic events after bioresorbable scaffold implantation: a systematic review and meta-analysis of randomized clinical trials. Eur Heart J. https://doi.org/10.1093/eurheartj/ehx155

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    2017-07-28 paperyu

    #支架植入#

    0

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    2017-11-10 膀胱癌

    #生物可吸收#

    0

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    2018-02-12 liao1619

    #可吸收#

    0

  4. 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createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Fri Nov 10 04:49:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030862, encodeId=400f20308620b, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Mon Feb 12 21:49:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946070, encodeId=610219460e006, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-06-08 xiaoyang_ambs

    #血栓事件#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Fri Nov 10 04:49:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030862, encodeId=400f20308620b, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Mon Feb 12 21:49:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946070, encodeId=610219460e006, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-05-07 cuiyejia

    学习了，谢谢

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, 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likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-04-26 cuiyejia

    学习了，谢谢分享

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, 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likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-04-26 zhaojie88

    #ART#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Fri Nov 10 04:49:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030862, encodeId=400f20308620b, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Mon Feb 12 21:49:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946070, encodeId=610219460e006, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-04-26 jiyangfei

    #植入#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Fri Nov 10 04:49:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030862, encodeId=400f20308620b, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Mon Feb 12 21:49:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946070, encodeId=610219460e006, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-04-26 slcumt

    #HEART#

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1935155, encodeId=524c193515586, content=<a href='/topic/show?id=49455e1086e' target=_blank style='color:#2F92EE;'>#支架植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57108, encryptionId=49455e1086e, topicName=支架植入)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Fri Jul 28 09:49:00 CST 2017, time=2017-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076859, encodeId=b61320e6859d6, content=<a href='/topic/show?id=0b93692e416' target=_blank style='color:#2F92EE;'>#生物可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69274, encryptionId=0b93692e416, topicName=生物可吸收)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Fri Nov 10 04:49:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030862, encodeId=400f20308620b, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Mon Feb 12 21:49:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946070, encodeId=610219460e006, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Thu Jun 08 09:49:00 CST 2017, time=2017-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194953, encodeId=3c501949538d, content=学习了，谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Sun May 07 10:50:52 CST 2017, time=2017-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190847, encodeId=dcd819084eb8, content=学习了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Wed Apr 26 19:52:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356234, encodeId=27c81356234b1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520357, encodeId=6b7c152035e9a, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562492, encodeId=3433156249219, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Apr 26 07:49:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190371, encodeId=f6061903e196, content=还可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzXprUCFDMuY1SXH96r8MdtExF6fhSNLulicdUBcsodicYROXqf5icqDWFAOicfEqYtDcjL6HvrQrvmO1/0, createdBy=db841700299, createdName=克勤, createdTime=Tue Apr 25 07:23:34 CST 2017, time=2017-04-25, status=1, ipAttribution=)]
    2017-04-25 克勤

    还可以

    0

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