SCI REP:细颗粒物空气污染与缺血性脑卒中首次入院相关!

2017-06-20 xing.T MedSci原创

由此可见,在中国北京,短期暴露于PM2.5与缺血性卒中首次入院之间存在相关性。

近日,Scientific reports 杂志上发表了一篇来自中国学者的研究文章,该研究的主要目的是评估周围环境中可入肺细颗粒物(PM2.5)短期变化与缺血性脑卒中首次入院之间的相关性。

研究人员确定了在2010年1月1日到2012年6月30日期间来自于北京医务人员索赔数据中的63956例首次缺血性脑卒中住院患者。研究人员应用广义加法泊松模型探讨了PM2.5与缺血性卒中入院之间的相关性。研究人员还探讨了被年龄和性别改变的风险效应。

研究人员发现PM2.5与缺血性脑卒中入院之间的暴露-响应关系是近似线性的,在低浓度(<100 μg/m3)时,具有相对稳定的反应;在高浓度时,具有较为陡峭的反应。同一天PM2.5浓度增加10 μg/m3与当天缺血性卒中入院增加0.31%(95%可信区间为0.17-0.45%,P<1.57×10-5)相关。该相关性在延迟1、2、3、0-2和0-4天也具有统计上的显著差异。亚组分析表明,在超过65岁的患者和不足65岁的患者之间之间或男性患者与女性患者之间没有差异。

由此可见,在中国北京,短期暴露于PM2.5与缺血性卒中首次入院之间存在相关性。

原始出处:

Yaohua Tian,et al. Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-04312-5

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createdBy=ce6131283360, createdName=ms8435843352634314, createdTime=Mon Jan 01 01:36:00 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807052, encodeId=dfad180e05239, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Tue Jul 25 07:36:00 CST 2017, time=2017-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721778, encodeId=ee831e2177893, content=<a href='/topic/show?id=a15a100e2229' target=_blank style='color:#2F92EE;'>#颗粒物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100722, encryptionId=a15a100e2229, topicName=颗粒物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=106533095611, createdName=lisa449, createdTime=Fri Jan 05 07:36:00 CST 2018, time=2018-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472550, encodeId=072914e255074, content=<a href='/topic/show?id=ba4a6436107' target=_blank style='color:#2F92EE;'>#污染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Thu Jun 22 09:36:00 CST 2017, time=2017-06-22, status=1, ipAttribution=), 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createdTime=Tue Jun 20 21:35:53 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213218, encodeId=4a9e21321864, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Jun 20 20:38:16 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213193, encodeId=4d8e21319348, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Jun 20 19:28:42 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2018-01-05 lisa449
  5. 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  6. 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time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2017-06-21 jianzhang20

    雾霾的危害需要综合的研究,特别是进入血液后的影响

    0

  7. 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createdTime=Tue Jun 20 21:35:53 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213218, encodeId=4a9e21321864, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Jun 20 20:38:16 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213193, encodeId=4d8e21319348, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Jun 20 19:28:42 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2017-06-20 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

  8. 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createdTime=Tue Jun 20 21:35:53 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213218, encodeId=4a9e21321864, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Jun 20 20:38:16 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213193, encodeId=4d8e21319348, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Jun 20 19:28:42 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2017-06-20 dhzzm

    学习了分享了

    0

  9. 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time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2017-06-20 中医痴

    不错的,学习了,谢谢分享!

    0

  10. 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createdTime=Tue Jun 20 21:35:53 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213218, encodeId=4a9e21321864, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Jun 20 20:38:16 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213193, encodeId=4d8e21319348, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Jun 20 19:28:42 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213188, encodeId=2ce021318818, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 20 19:25:34 CST 2017, time=2017-06-20, status=1, ipAttribution=)]
    2017-06-20 1dd8aa01m06(暂无匿称)

    学习了很好的内容

    0

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