eLife:现代人为什么越来越焦虑?

2018-05-10 小通 生物通

过度概括,也许是某些人害怕或避免经历未发生的、实际并不危险的事情的原因。这种过度回避被认为是焦虑、强迫症、慢性疼痛和抑郁症的一个重要因素


过度概括,也许是某些人害怕或避免经历未发生的、实际并不危险的事情的原因。这种过度回避被认为是焦虑、强迫症、慢性疼痛和抑郁症的一个重要因素。

“如果吃某种食物会使你生病,那么你未来可能会避免吃类似的或闻起来像的食物,”剑桥大学助理研究员、这篇《eLife》文章的第一作者Agnes Norbury说。这种“概括”能力是人类的重要生存技能。但是过度概括,也许是某些人害怕或避免经历未发生的、实际并不危险的事情的原因。这种过度回避被认为是焦虑、强迫症、慢性疼痛和抑郁症的一个重要因素。“我们想知道人类如何决定是否回避特定情况,这些信息如何在大脑中生成,以及负面事件‘概括(generalize)’越多的人是否表现得更焦虑。”

Norbury和她的团队应征了两组志愿者,对其中26人进行实验室核磁共振扫描,482人通过网络进行测试。受试者在电脑屏幕上会看到一些花纹,一些代表安全,一些代表危险。为了避免危险花纹,参与者可以点击“逃生”按钮。如果他们不这样做,在实验室的志愿者就要受到电击,同时,在线测试的参与者会失去“金币(钱)”。但是,点击“逃生”按钮也要付出代价,在测试的最后会受到额外电击或损失更多的钱(经常回避不能减轻痛苦)。

测试中,研究人员观察受试者过度“概括”和点击逃生按钮现象。当受试者看到其他人痛苦或收益损失相关图像时,研究人员使用数学模型重建受试者如何决策避免这种情况,再将其与脑部扫描和心理症状问卷调查相结合。

他们发现,与安全或中性的结果相比,人们更喜欢“概括”负面事件。视觉、恐惧反应和安全学习等不同脑区都出现活动。此外,从负面事件(疼痛或收益受损)概括越多的受试者陷入了更多焦虑感和侵扰思想(进入你的大脑、违背你的意志,让你很难摆脱的消极想法)。

“我们希望这些数据有助于深入探讨有关焦虑的思维过程,”通讯作者Ben Seymour说。“我们的研究结果表明,将复杂的行为过程(如概括)分成可被检测的组分(比如脑活动和症状)进行分析是可行的。通过了解不同案例引起症状的原因,未来,我们将能更有效地为焦虑人群定制治疗方案。”

原始出处:

Agnes Norbury et al.Value generalization in human avoidance learning.eLife.RESEARCH ARTICLE May 8, 2018

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    2018-09-13 膀胱癌
  2. 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    2018-09-09 clmlylxy
  3. 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    2018-05-14 易水河

    现代版的丛林困惑

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Mon May 14 03:18:29 CST 2018, time=2018-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314876, encodeId=038e3148e6c9, content=学了, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Mon May 14 03:18:25 CST 2018, time=2018-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314096, encodeId=51a3314096df, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri May 11 06:58:23 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050457, encodeId=cf07105045e8e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Fri May 11 02:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313942, encodeId=3e913139426e, content=生活.工作紧张孕育焦虑., beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-14 哈哈869

    学了

    0

  5. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri May 11 06:58:23 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050457, encodeId=cf07105045e8e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Fri May 11 02:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313942, encodeId=3e913139426e, content=生活.工作紧张孕育焦虑., beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], 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    2018-05-14 哈哈869

    学了

    0

  6. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri May 11 06:58:23 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050457, encodeId=cf07105045e8e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Fri May 11 02:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313942, encodeId=3e913139426e, content=生活.工作紧张孕育焦虑., beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-11 186****0580(小山羊)

    学习了谢谢了

    0

  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri May 11 06:58:23 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050457, encodeId=cf07105045e8e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Fri May 11 02:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313942, encodeId=3e913139426e, content=生活.工作紧张孕育焦虑., beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-11 张新亮1853311252142e2fm

    好文献学习了

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri May 11 06:58:23 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050457, encodeId=cf07105045e8e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Fri May 11 02:11:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313942, encodeId=3e913139426e, content=生活.工作紧张孕育焦虑., beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-11 kafei

    了解一下

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-11 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

  10. 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 10 23:55:40 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-10 1e0f8808m18(暂无匿称)

    生活.工作紧张孕育焦虑.

    0

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心理疾病成为研究生教育中越来越令人担忧的问题,最近一项调查的数据可能会促使学术界和政策制定者考虑采取干预措施。

Brain Sci:适当程度的焦虑能够提升记忆力

对于焦虑症患者,似乎很难胜任日常的工作。在最糟糕的情况下,焦虑甚至会导致睡眠困难、心悸,以至于无法离开房间。

SCI REP:低血维生素D水平与透析儿童和青少年的焦虑有关!

由此可见,该研究的结果表明低血清维生素D水平与接受透析的儿童和青少年焦虑之间存在独立的相关性,需要在今后的实验和临床研究中进一步加以证实。

Maturitas:在老年人中,言语和高频率听力损失以及抑郁、焦虑和压力之间的相关性研究

年龄相关的听力损失(ARHL)和抑郁被认为是导致老年人残疾的主导原因。最近,有研究人员进行了一个代表性的研究,调查了老年人中言语严重度和高频听力损失与抑郁、焦虑和压力之间的关系。研究包括了151名参与者(73名男性和78名女性,平均年龄为64.44±10.77岁)。研究人员根据他们的更好的耳朵听力(0.5, 1, 2和4kHz)和高频率(6和8kHz)听力阈值,将他们分成了3个小组:正常听力组、轻