IJERPH:南方医大邹和群发现围绝经期女性代谢综合征或与慢性肾脏疾病有关

2013-09-06 佚名 丁香园

为了探讨围绝经期女性代谢综合征(MetS)与慢性肾脏疾病(CKD)之间的关系,来自南方医科大学第三附属医院邹和群教授及其团队进行了一项研究(Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women),该研究发现年龄50到60岁的围绝经期女性MetS与CKD相关。该研究结果发

为了探讨围绝经期女性代谢综合征(MetS)与慢性肾脏疾病(CKD)之间的关系,来自南方医科大学第三附属医院邹和群教授及其团队进行了一项研究(Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women),该研究发现年龄50到60岁的围绝经期女性MetS与CKD相关。该研究结果发表在2013年8月International Journal of Environmental Research and Public Health杂志上,该杂志影响因子为1.998.该研究中,从2012年6月至2012年10月在珠海市进行了一项横断面研究。685例围绝经期女性纳入该研究。所有受试者被分为三组:组1,40岁<年龄<50岁;组2,50岁<年龄<60岁;组3,60岁<年龄<65岁。【原文下载

该研究结果表明,在所有受试者的未校正分析中,MetS与CKD相关。校正潜在的混杂因素后,MetS的CKD比值比为2.66.组1和组3中MetS与CKD无关。组2未校正分析中,MetS与CKD相关。校正潜在混杂因素后,MetS与CKD显著相关。MetS的CKD比值比为6.79.组1和组3中血压升高、空腹血糖升高、腹型肥胖、低高密度脂蛋白胆固醇(HDL-C)、甘油三酯升高与CKD无关。组2中血压升高与CKD相关。校正潜在混在因素后,血压升高与CKD无关。组2中空腹血糖升高与CKD相关。校正潜在混在因素后,空腹血糖升高与CKD无关。组2中腹型肥胖、低HDL-C、甘油三酯升高与CKD无关。

该研究发现,在年龄50到60岁的围绝经期女性中,MetS与CKD相关。而年龄40到50岁和年龄60到65岁的、围绝经期女性的MetS与CKD无关。

原文下载

Li Y, Zhao L, Chen Y, Liu A, Liu X, Shao X, Zhang Y, Wang H, Wang X, Li B, Deng K, Liu Q, Holthöfer H, Zou H.Association between Metabolic Syndrome and Chronic Kidney Disease in Perimenopausal Women.Int J Environ Res Public Health. 2013 Aug 30;10(9):3987-97.

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    2013-09-08 海豹
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