盘点:2018年度肿瘤相关新指南汇总(一)

2018-08-16 shaosai MedSci原创

【盘点】2018年度肿瘤相关新指南汇总(一)

NCCN临床实践指南:急性髓性白血病(2018.V1)

指南名称:NCCN临床实践指南:急性髓性白血病(2018.V1)

英文标题:NCCN Clinical Practice Guidelines in Oncology:Acute Myeloid Leukemia(Version 1.2018)

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2018-2-7

简要介绍:

2018年2月,美国国家综合癌症网络(NCCN)发布了急性髓性白血病指南2018年第1版,指南主要内容包括:

指南更新摘要

急性白血病和诊断研究评估(AML-1)

APL,诱导治疗(AML-2)

APL,诱导治疗和巩固治疗(AML-3)

APL,巩固后治疗(AML-6)

APL,复发治疗(AML-7)

AML,标准剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-8)

AML,大剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-9)

AML,缓解后治疗(年龄<60y)(AML-10)

AML,诱导治疗(年龄>60y)(AML-11)

AML,标准剂量阿糖胞苷诱导后治疗(年龄≥60y)(AML-12)

AML,缓解后治疗(年龄≥60y) (AML-13)

AML,监测(AML-14)

AML,复发/难治性疾病的治疗(AML-14)

基于验证细胞遗传学和分子异常风险状态(AML-A)

CNS淋巴瘤的评估和治疗(AML-B)

支持性治疗(AML-C)

急性髓系白血病反应标准(AML-D)

治疗期间监测(AML-E)

复发/难治性疾病的治疗(AML-F)


NCCN临床实践指南:急性髓性白血病(2018.V2)

指南名称:NCCN临床实践指南:急性髓性白血病(2018.V2)

英文标题:NCCN Clinical Practice Guidelines in Oncology:Acute Myeloid Leukemia(Version 2.2018)

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2018-8-1

简要介绍:2018年8月,美国国家综合癌症网络(NCCN)发布了急性髓性白血病指南2018年第2版,指南主要内容包括:

指南更新摘要

急性白血病和诊断研究评估(AML-1)

APL,诱导治疗(AML-2)

APL,诱导治疗和巩固治疗(AML-3)

APL,巩固后治疗(AML-6)

APL,复发治疗(AML-7)

AML,标准剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-8)

AML,大剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-9)

AML,缓解后治疗(年龄<60y)(AML-10)

AML,诱导治疗(年龄>60y)(AML-11)

AML,标准剂量阿糖胞苷诱导后治疗(年龄≥60y)(AML-12)

AML,缓解后治疗(年龄≥60y) (AML-13)

AML,监测(AML-14)

AML,复发/难治性疾病的治疗(AML-14)

基于验证细胞遗传学和分子异常风险状态(AML-A)

CNS淋巴瘤的评估和治疗(AML-B)

支持性治疗(AML-C)

急性髓系白血病反应标准(AML-D)

治疗期间监测(AML-E)

复发/难治性疾病的治疗(AML-F)


NCCN临床实践指南:急性髓性白血病(2017.V3)

指南名称:NCCN临床实践指南:急性髓性白血病(2017.V3)

英文标题:NCCN Clinical Practice Guidelines in Oncology:Acute Myeloid Leukemia(Version 3.2017)

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2017-6-6

简要介绍:

2017年6月,美国国家综合癌症网络(NCCN)发布了急性髓性白血病指南2017年第3版,指南主要内容包括: 指南更新摘要 急性白血病和诊断研究评估(AML-1) APL,诱导治疗(AML-2) APL,巩固后治疗(AML-5) APL,复发治疗(AML-7) AML,治疗反应(年龄<60y)(AML-7) AML,标准剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-8) AML,大剂量阿糖胞苷诱导缓解后治疗(年龄<60y)(AML-9) AML,缓解后治疗(年龄<60y)(AML-10) AML,诱导治疗(年龄>60y)(AML-11) AML,标准剂量阿糖胞苷诱导后治疗(年龄≥60y)(AML-12) AML,缓解后治疗(年龄≥60y) (AML-13) AML,监测(AML-14) AML,复发/难治性疾病的治疗(AML-14) 基于验证细胞遗传学和分子异常风险状态(AML-A) CNS淋巴瘤的评估和治疗(AML-B) 支持性治疗(AML-C) 急性髓系白血病反应标准(AML-D) 治疗期间监测(AML-E) 复发/难治性疾病的治疗(AML-F)


NCCN临床实践指南:慢性髓性白血病(2019.V1-4)

指南名称:NCCN临床实践指南:慢性髓性白血病(2019.V1)

英文标题:NCCN Clinical Practice Guidelines in Oncology:Chronic Myeloid Leukemia (Version 1.2019)

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2018-8-1

简要介绍:2018年8月,美国国家综合癌症网络(NCCN)发布了慢性髓性白血病指南2019年第1版,指南主要内容涉及:

更新摘要

检查

慢性期CML:初始治疗治疗

治疗响应时间表,临床注意事项以及治疗方案

进展期CML:初始治疗

基于BCR-ABL1基因突变的治疗方案

造血干细胞移植

风险评估表

加速阶段定义

爆发阶段定义

TKI治疗反映监测反映和突变分析

血液,遗传学和分析反映和复发的标准

TKI治疗停药标准

各种治疗药物毒性的管理


中医儿科临床诊疗指南·小儿口疮(修订)

指南名称:中医儿科临床诊疗指南·小儿口疮(修订)

发布机构:中医相关专家组(统称)

发布日期:2018-7-30

简要介绍:

完成文献检索、文献评价及文献总结,2 轮专家问卷调查,专家论证会,专家质量方法学评价和临床一致性评价,形成《中医儿科临床诊疗指南·小儿口疮》修订稿,提出小儿口疮诊疗指南的范围、术语和定义、诊断、辨证、治疗、预防和调护,供中医儿科行业使用。


2018 ESMO临床实践指南:成人癌痛的管理

指南名称:2018 ESMO临床实践指南:成人癌痛的管理

英文标题:Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines

发布机构:欧洲肿瘤内科学会(ESMO,European Society for Medical Oncology)

发布日期:2018-7-23

简要介绍:

2018年,欧洲肿瘤内科学会(ESMO)发布了成人癌痛的管理指南,用以替代2012年版指南。癌症患者疼痛常见,尤其是在晚期癌症的患者当中。本文主要内容涉及成人癌痛的评估,疼痛治疗原则,以及各种类型疼痛的管理。


2018 ESMO临床实践指南:癌症患者贫血和铁缺乏的管理

指南名称:2018 ESMO临床实践指南:癌症患者贫血和铁缺乏的管理

英文标题:Management of anaemia and iron deficiency in patients with cancer: ESMO Clinical Practice Guidelines.

发布机构:欧洲肿瘤内科学会(ESMO,European Society for Medical Oncology)

发布日期:2018-2-20

简要介绍:

2018年2月,欧洲肿瘤内科学会(ESMO)发布了癌症患者贫血和铁缺乏的管理指南。贫血和缺铁是实体肿瘤和血液恶性肿瘤,尤其是接受化疗药物治疗患者最常见的并发症,本文主要针对贫血的评估以及补铁治疗方法提出指导建议,主要目的是优化癌症患者贫血和铁缺乏的管理。


重视癌症患者贫血,早期筛查与治疗铁缺乏——欧洲《成年癌症患者铁缺乏的管理意见书》解读

指南名称:重视癌症患者贫血,早期筛查与治疗铁缺乏——欧洲《成年癌症患者铁缺乏的管理意见书》解读

发布日期:2018-1-30

简要介绍:

贫血是肿瘤患者常见的并发症,而铁缺乏是其最常见的病因之一。本文对欧洲肿瘤及血液学专家组2017 年发布的《成年癌症患者铁缺乏的管理意见书》进行了解读,并与国内外肿瘤相关贫血指南、既往文献进行对比与总结,重点强调:应在癌症患者中早期定期评估和监测铁参数,早期识别和治疗贫血,以促红细胞生成类药物和铁剂补充作为绝对性铁缺乏和功能性缺铁的治疗基石,减少不必要的输血。


NCCN临床实践指南:癌症和化疗诱导的贫血

指南名称:NCCN临床实践指南:癌症和化疗诱导的贫血(2018.V1)

英文标题:NCCN clinical practice guidelines in Oncology:Cancer- and Chemotherapy-Induced Anemia(2018.V1)

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2017-6-23

简要介绍:2017年6月,美国国家综合癌症网络(NCCN)发布了癌症和化疗诱导的贫血指南2018年第1版,指南主要内容涉及:

指南更新摘要

贫血评估

急诊首次输血适应症和风险评估

ESA使用与红细胞输注的风险和目标

ESA应用特殊类别考虑

缺铁评估

红细胞输注的适应症

红细胞生成治疗

肠外铁剂

拒绝输血的癌症和化疗诱导的贫血患者的管理


2018 ESE临床实践指南:成人肾上腺皮质癌的管理

指南名称:2018 ESE临床实践指南:成人肾上腺皮质癌的管理

英文标题:European Society of Endocrinology Clinical Practice Guidelines on the Management of Adrenocortical Carcinoma in Adults, in collaboration with the European Network for the Study of Adrenal Tumors.

发布机构:欧洲内分泌学会(ESE,European Society of Endocrinology)

发布日期:2018-7-24

简要介绍:

2018年7月,欧洲内分泌学会(ESE)发布了成人肾上腺皮质癌的管理指南,肾上腺皮质癌(ACC) 是一罕见的恶性肿瘤,本文的主要目的是为临床医生提供关于肾上腺皮质癌管理的实践指导建议。内容涉及ACC的诊断和疑似ACC,疑似局部ACC的手术治疗,病例检查,分期和预后因素,影像学检查和评估,辅助治疗,复发/晚期疾病恶管理,特殊情况的管理等。


NCCN临床实践指南:神经内分泌肿瘤和肾上腺瘤

指南名称:NCCN临床实践指南:神经内分泌肿瘤和肾上腺瘤(2018.V1)

英文标题:NCCN Clinical Practice Guidelines in Oncology:Neuroendocrine and Adrenal Tumors( Version 1.2018 )

发布机构:美国国家综合癌症网络(NCCN,National Comprehensive Cancer Network)

发布日期:2018-3-29

简要介绍:

2018年3月,美国国家综合癌症网络(NCCN)发布了神经内分泌肿瘤和肾上腺瘤2018年第1版,该指南是对2017年第3版神经内分泌肿瘤的更新,指南名称由原来的神经内分泌肿瘤变为神经内分泌肿瘤和肾上腺瘤。


胰腺癌综合诊治指南(2018版)外科相关部分解读

指南名称:胰腺癌综合诊治指南(2018版)外科相关部分解读

发布日期:2018-6-30

简要介绍:

胰腺癌的诊治现状不容乐观,临床治疗模式亟需结合肿瘤学的新理念,在多学科协作、个体化诊疗以及多中心跨区域的临床试验中不断进行修正。笔者结合最新的中国抗癌协会胰腺癌专业委员会发布的胰腺癌综合诊治指南(2018 版)(下文简称新版指南),就胰腺癌外科综合治疗的热点问题加以解读。

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#插入话题
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  2. [GetPortalCommentsPageByObjectIdResponse(id=1923368, encodeId=1e4e192336818, content=<a href='/topic/show?id=1408583e45d' target=_blank style='color:#2F92EE;'>#新指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58374, encryptionId=1408583e45d, topicName=新指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Wed May 08 19:15:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339114, encodeId=d9b233911427, content=肿瘤指南,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Fri Aug 17 08:50:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339103, encodeId=66c033910329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Aug 17 08:02:02 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339066, encodeId=a77733906630, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri Aug 17 03:43:12 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339047, encodeId=efd233904e71, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Aug 16 23:50:33 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339031, encodeId=f142339031b0, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Aug 16 23:36:33 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
    2018-08-17 liumin1987

    肿瘤指南,学习了。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1923368, encodeId=1e4e192336818, content=<a href='/topic/show?id=1408583e45d' target=_blank style='color:#2F92EE;'>#新指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58374, encryptionId=1408583e45d, topicName=新指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Wed May 08 19:15:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339114, encodeId=d9b233911427, content=肿瘤指南,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Fri Aug 17 08:50:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339103, encodeId=66c033910329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Aug 17 08:02:02 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339066, encodeId=a77733906630, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri Aug 17 03:43:12 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339047, encodeId=efd233904e71, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Aug 16 23:50:33 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339031, encodeId=f142339031b0, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Aug 16 23:36:33 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
    2018-08-17 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1923368, encodeId=1e4e192336818, content=<a href='/topic/show?id=1408583e45d' target=_blank style='color:#2F92EE;'>#新指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58374, encryptionId=1408583e45d, topicName=新指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Wed May 08 19:15:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339114, encodeId=d9b233911427, content=肿瘤指南,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Fri Aug 17 08:50:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339103, encodeId=66c033910329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Aug 17 08:02:02 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339066, encodeId=a77733906630, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri Aug 17 03:43:12 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339047, encodeId=efd233904e71, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Aug 16 23:50:33 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339031, encodeId=f142339031b0, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Aug 16 23:36:33 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
    2018-08-17 kafei

    了解一下谢谢

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1923368, encodeId=1e4e192336818, content=<a href='/topic/show?id=1408583e45d' target=_blank style='color:#2F92EE;'>#新指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58374, encryptionId=1408583e45d, topicName=新指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Wed May 08 19:15:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339114, encodeId=d9b233911427, content=肿瘤指南,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Fri Aug 17 08:50:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339103, encodeId=66c033910329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Aug 17 08:02:02 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339066, encodeId=a77733906630, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri Aug 17 03:43:12 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339047, encodeId=efd233904e71, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Aug 16 23:50:33 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339031, encodeId=f142339031b0, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Aug 16 23:36:33 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
    2018-08-16 清风拂面

    谢谢分享学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1923368, encodeId=1e4e192336818, content=<a href='/topic/show?id=1408583e45d' target=_blank style='color:#2F92EE;'>#新指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58374, encryptionId=1408583e45d, topicName=新指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ac782500066, createdName=12498768m13(暂无昵称), createdTime=Wed May 08 19:15:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339114, encodeId=d9b233911427, content=肿瘤指南,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Fri Aug 17 08:50:55 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339103, encodeId=66c033910329, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Aug 17 08:02:02 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339066, encodeId=a77733906630, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Fri Aug 17 03:43:12 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339047, encodeId=efd233904e71, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Aug 16 23:50:33 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339031, encodeId=f142339031b0, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Aug 16 23:36:33 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
    2018-08-16 惠映实验室

    学习了,谢谢分享。

    0

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女性,66岁。右侧腰痛伴间断性肉眼血尿10余天,疼痛为阵发性,可自行缓解,疼痛发作时有发热

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抗PD-1抗体在治疗肿瘤方面显示出值得瞩目的前景,包括转移性黑素瘤。但是,患者的反应率很低。因此,我们需要更好地了解PD-L1介导的免疫逃避,以预测患者反应,并提高治疗效果。