Cell Rep:重大突破!科学家找到了治疗高血压的全新机制

2017-11-15 佚名 medicalxpress

众所周知,含盐量太高的饮食对身体有很多不健康的影响,然而,虽然膳食中盐摄入量与血压相关,但是盐与高血压的机制并不确定。发表于《Cell Reports》杂志上的研究指出了引起炎症和高血压的多余钠摄入量的另一条其他通路。

众所周知,含盐量太高的饮食对身体有很多不健康的影响,然而,虽然膳食中盐摄入量与血压相关,但是盐与高血压的机制并不确定。发表于《Cell Reports》杂志上的研究指出了引起炎症和高血压的多余钠摄入量的另一条其他通路。

在此次研究中,研究人员发现,钠进入免疫系统树突细胞,最终会生产超氧化物和免疫原性蛋白质的形成,盐刺激树突细胞,产生炎性因子,并且激活T细胞,这也就是含盐量高的食物对身体不健康的原因。

然而,实验过程中,研究人员也发现了不一样的机制,研究人员以小鼠作为研究对象,通过高钠饮食T细胞被激活,接下来,研究人员将激活的T细胞转移到老鼠体内,小鼠的血压没有增加。

高血压是最常见的慢性病,也是心脑血管病最主要的危险因素,近些年来,对于高血压的标准在不断调整,据报道,最新的高血压标准已经调整到130毫米汞柱,其实就是为了让大家提高对血压的重视,及早的预防和避免大病的到来。

研究小组负责人在报告中表示:“这一结果很可能带来预防和治疗高血压的新方法,我们可以想办法把引起高血压和炎症的细胞阻隔在外,也就是说,阻止钠进入树突细胞可能带来意想不到的抗氧化和消炎作用,也能成为对抗高血压的新方法。”

原始出处:

Natalia R. Barbaro, Jason D. Foss, Dmytro O. Kryshtal, et.al. Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension. Cell Reports

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    2018-01-03 维他命
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    2017-11-17 jihuaijun1112

    学习学习学习

    0

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    2017-11-16 天涯183

    非常好的文章.学习了

    0

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    2017-11-16 wangvase

    直接减少钠盐摄入不是更好?

    0

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    2017-11-16 明天会更好!

    阅读.谢谢分享.

    0

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    2017-11-16 yfjms

    学习

    0

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    2017-11-16 戒馋,懒,贪

    谢谢分享

    0

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