PLOS ONE:皮质醇指数对心理社会和身体健康的影响

2019-04-05 海北 MedSci原创

在静止条件下对皮质醇的调节被广泛用于评估身体和心理状态,但由于可能的评估的多样性(例如,累积水平;昼夜模式),一次只考虑一个或几个会妨碍人们的理解和解释。

在静止条件下对皮质醇的调节被广泛用于评估身体和心理状态,但由于可能的评估的多样性(例如,累积水平;昼夜模式),一次只考虑一个或几个会妨碍人们的理解和解释。此外,大多数关于皮质醇调节的研究都集中在负面平衡的经历上。

最近的一项研究检查了皮质醇指数之间的相互关系,及其对不同心理社会和健康因素(包括积极功能)中解释的方差的相对贡献。

该研究的数据来自中年和老年人(N = 513;男性占47.2%)。研究人员在尿液(过夜)和唾液(静息和连续4天)中评估皮质醇,并通过自我报告评估正面和负面的社会心理和健康因素。

除了检查皮质醇指数之间的关联之外,研究人员还使用相对权重分析来确定哪些指数与特定心理社会因素最强烈地相关。

结果显示,指数之间的相互关系是弱到中等的,这表明它们测量了下丘脑 - 垂体 - 轴活动的不同方面。由皮质醇指数解释的心理社会和健康因素(R2)的总体差异范围为0.01至0.07。在这个解释的方差中,相对权重分析显示,醒来皮质醇对享乐幸福感(32.1%-38.2%),睡前皮质醇与抑郁相关因子(32.1%-46.9%),皮质醇唤醒对eudaimonic幸福感的反应(35.8%-50.5%),皮质醇斜率与感知压力(29.2%),尿皮质醇与物理因素(38.5%和62.7%)的变异贡献最大。

因此,阳性和阴性因素与很大程度上不重叠的皮质醇指数有关。这项研究阐明了皮质醇指数与精神和身体健康的各个方面之间的细微差别的联系,促进了对下丘脑 - 垂体 - 轴活动在健康中的复杂作用的理解。


原始出处:

Rector JL et al. Relative sensitivity of cortisol indices to psychosocial and physical health factors. PLOS ONE, 2019; doi: 10.1371/journal.pone.0213513. eCollection 2019.


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    2021-03-14 ms2000000239662574

    皮质醇水平只能解释一部分的心理症状。

    0

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    2019-04-06 百草

    学习

    0

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    2019-04-05 gcwu82

    很好学习了

    0

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