AIM:脂肪摄入无限制的地中海饮食对健康也是有益的

2016-07-19 崔倩 译 MedSci原创

地中海饮食可能比典型的西方饮食更健康。该研究的目的是总结脂肪摄入不受限制的地中海饮食与其他饮食相比对于对成年人健康影响的文献。研究人员检索了1990-2016年的vid MEDLINE, CINAHL, 和Cochrane Library的研究。研究人员选择的研究为有100人或以上的对照试验,对于死亡率,心血管,高血压,糖尿病等结果至少随访1年,以及癌症结果的队列研究。由1名研究者提取数据,由另外

地中海饮食可能比典型的西方饮食更健康。该研究的目的是总结脂肪摄入不受限制的地中海饮食与其他饮食相比对于对成年人健康影响的文献。

研究人员检索了1990-2016年的vid MEDLINE, CINAHL, 和Cochrane Library的研究。

研究人员选择的研究为有100人或以上的对照试验,对于死亡率、心血管、高血压糖尿病等结果至少随访1年,以及癌症结果的队列研究。

由1名研究者提取数据,由另外两名评价者进行验证,评估偏差和证据强度的风险。

研究人员发现,在两个主要的预防试验中,在饮食组之间的全因死亡率无差异。一个大型的初级预防试验发现,地中海式饮食会减少主要心血管事件(危险比[HR],0.71 [95%CI,0.56至0.90])、乳腺癌(HR,0.43 [CI,0.21至0.88])和糖尿病(HR,0.70 [CI,0.54至0.92])的发病率。一级预防队列研究的汇总分析表明,与最低分位数相比,坚持地中海饮食的最高分位数与总癌症死亡事件(风险比率[RR],0.86 [CI,0.82至0.91]; 13项研究)和总的癌症(RR,0.96 [CI,0.95至0.97]; 3项研究)和结肠癌(RR,0.91 [CI,0.84至0.98; 9项研究])的发生率降低相关。3项二级预防研究报告了心血管事件,1项研究发现地中海饮食可降低复发性心肌梗死和心血管死亡的风险。还有不一致的,最小的,或没有任何证据有关的任何其他结果,包括坚持,高血压,认知功能,肾脏疾病,类风湿关节炎,生活质量。

该研究的限制性为纳入的试验较少;许多研究的中等风险的偏见评级;较低或不足的证据的结果;异质性饮食定义和构成。

有限的证据表明,对脂肪的摄入量没有限制的地中海式饮食可降低心血管事件,乳腺癌和2型糖尿病的发病率,但可能不会影响全因死亡率。

原始出处:

Hanna E. Bloomfield,Eva Koeller,Nancy Greer,et al.Effects on Health Outcomes of a Mediterranean Diet With No Restriction on Fat Intake,Ann Intern Med,2016.7.19

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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

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    2016-08-02 The one 00000

    不饱和脂肪酸比较多

    0

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    2016-07-21 wgx311
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    2016-07-19 doctorJiangchao

    继续学习

    0