SCI REP:重度主动脉瓣狭窄患者死亡原因分析!

2017-11-07 xing.T MedSci原创

这些发现强调了密切监测非心脏病合并症以及心衰和猝死的重要性,这样以改善重症AS患者的死亡率。

严重主动脉瓣狭窄(AS)患者是否因AS相关原因而死亡是这些患者治疗管理的一个重要问题。近日,Scientific reports 杂志上发表了一篇研究文章,研究人员利用来自于日本多中心登记处当前的数据,对重症AS患者的死亡原因进行评估,并找出与非心源性死亡相关的因素。

研究人员招募了3815例连续就诊的患者,中位随访1176天,其中1449例死亡患者中,647例(55.3%)患者死于心脏病,802例(44.7%)患者死于非心脏原因。心力衰竭(HF)(25.7%)和猝死(13%)是导致心源性死亡最常见的原因,而感染(13%)和恶性肿瘤(11.1%)是导致死亡最主要的非心脏原因。

根据治疗方案,在最初的主动脉瓣置换术(AVR)组(n=1197)和保守治疗组(n=2618)中,感染是非心源性死亡最常见的原因,其次是恶性肿瘤。非心脏因素(年龄、男性、体重指数<22、糖尿病、既往卒中史、透析、贫血和恶性肿瘤)和心脏因素(心房颤动、射血分数<68%和初始AVR)均与非心源性死亡有关。

这些发现强调了密切监测非心脏病合并症以及心衰和猝死的重要性,这样以改善重症AS患者的死亡率。

原始出处:

Eri Minamino-Muta,et al. Causes of Death in Patients with Severe Aortic Stenosis: An Observational study.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-15316-6

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    2017-11-08 Drhzm308

    谢谢.学习了

    0

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    2017-11-08 飛歌

    学习一下看看再说

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1983543, encodeId=806e1983543f7, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Fri Mar 09 03:04:00 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774575, encodeId=9ce81e74575e0, content=<a href='/topic/show?id=a64f95e9906' target=_blank style='color:#2F92EE;'>#重度主动脉瓣狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95799, encryptionId=a64f95e9906, topicName=重度主动脉瓣狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=773e38606601, createdName=lxg964, createdTime=Fri Jun 29 00:04:00 CST 2018, time=2018-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903521, encodeId=67b91903521b1, content=<a href='/topic/show?id=c8aa6335ed5' target=_blank style='color:#2F92EE;'>#死亡原因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63357, encryptionId=c8aa6335ed5, topicName=死亡原因)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=570c172, createdName=tigerlr98, createdTime=Fri Jul 13 04:04:00 CST 2018, time=2018-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332467, encodeId=af0d133246e72, content=<a href='/topic/show?id=1dd6231822d' target=_blank style='color:#2F92EE;'>#主动脉瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Thu Nov 09 12:04:00 CST 2017, time=2017-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415220, encodeId=52771415220a5, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Thu Nov 09 12:04:00 CST 2017, time=2017-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=259629, encodeId=8f86259629d8, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Wed Nov 08 07:30:04 CST 2017, time=2017-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=259574, encodeId=49672595e498, content=学习一下看看再说, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Nov 08 00:16:56 CST 2017, time=2017-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=259568, encodeId=504425956811, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo4cyIbibqa2VuNGCKeyRxITYNqLTIaoFo3Jx2LSawp8yrFSs1CIXKv1jyXV97ecnxhhktGKkPP9onfJFZCbiayLgic/0, createdBy=3f1c1956638, createdName=1e127dd4m40(暂无匿称), createdTime=Tue Nov 07 23:53:23 CST 2017, time=2017-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=259524, encodeId=6f98259524cf, content=是很好的学习材料.不错.以后会多学习., beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Nov 07 21:32:38 CST 2017, time=2017-11-07, status=1, ipAttribution=)]
    2017-11-07 1e127dd4m40(暂无匿称)

    学习了

    0

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    2017-11-07 李东泽

    是很好的学习材料.不错.以后会多学习.

    0

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