Kidney Int:三种不同的家庭血液透析模式哪种更优呢?

2017-09-02 MedSci MedSci原创

家庭血液透析(HHD)具有许多益处,但是在比较不同的家庭血液透析模式时,相关的研究结果知之甚少。近期,一项发表在杂志Kidney Int上的研究比较了不同家庭血透模式的差异:每天接受短期HHD(2-3小时/次,每周5次),夜间HHD(6-8小时/次,每周 5次)和常规HHD(3-6小时/次,每周2-4次)。此项研究为1996-2012年加拿大HHD患者的全国代表性队列。主要研究结果是患者死亡或治疗

家庭血液透析(HHD)具有许多益处,但是在比较不同的家庭血液透析模式时,相关的研究结果知之甚少。


近期,一项发表在杂志Kidney Int上的研究比较了不同家庭血透模式的差异:每天接受短期HHD(2-3小时/次,每周5次),夜间HHD(6-8小时/次,每周 5次)和常规HHD(3-6小时/次,每周2-4次)。

此项研究为1996-2012年加拿大HHD患者的全国代表性队列。主要研究结果是患者死亡或治疗失败(定义为永久性返回中心内血液透析或进行腹膜透析),使用意向治疗分析和死亡检查治疗失败作为次要结果。

最终,此项研究分别由600名、508名和202名患者组成,分别接受常规、夜间和短暂的日常HHD。与夜间或短暂的HHD患者(分别为32%和31%)相比,常规HHD患者更有可能使用透析导管(43%)。

虽然点估计值有利于不同的疗法,但是对患者和中心因素进行多变量调整后,比较夜间与常规HHD患者(风险比0.83 [95%置信区间0.66-1.03])或者短期与常规HHD患者(风险比0.84,0.63-1.12),其死亡/治疗失败的相对危险度没有统计学上的显着降低。在有血管通路信息的患者中,接受夜间HHD的患者的死亡检查治疗生存期(0.75,0.57-0.98)有相对改善。

此项研究表明:在HHD患者的国家队列中,接受短期日常和夜间HHD的患者与接受常规HHD的患者相比,具有相似的患者/治疗生存期。

原始出处:
Tennankore KK, Na Y, et al. Short daily-, nocturnal- and conventional-home hemodialysis have similar patient and treatment survival. Kidney Int. 2017 Aug 23. pii: S0085-2538(17)30467-2. doi: 10.1016/j.kint.2017.06.014. 

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1262496, encodeId=ce6812624967e, content=<a href='/topic/show?id=a57589339a4' target=_blank style='color:#2F92EE;'>#血液透析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89339, encryptionId=a57589339a4, topicName=血液透析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19c567, createdName=habb, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1603072, encodeId=a70716030e217, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239764, encodeId=f1d4239e64f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Sat Sep 02 15:16:41 CST 2017, time=2017-09-02, status=1, ipAttribution=)]
    2017-09-04 habb
  2. [GetPortalCommentsPageByObjectIdResponse(id=1262496, encodeId=ce6812624967e, content=<a href='/topic/show?id=a57589339a4' target=_blank style='color:#2F92EE;'>#血液透析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89339, encryptionId=a57589339a4, topicName=血液透析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19c567, createdName=habb, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1603072, encodeId=a70716030e217, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239764, encodeId=f1d4239e64f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Sat Sep 02 15:16:41 CST 2017, time=2017-09-02, status=1, ipAttribution=)]
    2017-09-04 gwc389
  3. [GetPortalCommentsPageByObjectIdResponse(id=1262496, encodeId=ce6812624967e, content=<a href='/topic/show?id=a57589339a4' target=_blank style='color:#2F92EE;'>#血液透析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=13, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89339, encryptionId=a57589339a4, topicName=血液透析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19c567, createdName=habb, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1603072, encodeId=a70716030e217, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Mon Sep 04 01:42:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239764, encodeId=f1d4239e64f6, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Sat Sep 02 15:16:41 CST 2017, time=2017-09-02, status=1, ipAttribution=)]
    2017-09-02 184****9840

    学习了谢谢分享

    0