期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
Rheumatoid arthritis (RA) is a chronic autoimmune disease, which is compared to "immortal cancer" in industry. Currently, SYK, BTK, and JAK are the th......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
Nudeic acid aptamers are single-stranded oligonudeotides that may be evolved for affinity and specificity for their targets and can be easily produced......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
Considering the high cost of the production of semaglutide, which is currently the most promising antidiabetic drug especially for the treatment of ty......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
The thermoelectric properties of bismuth telluride thin film (BTTF) was tuned by inducing internal strain through a combination of combinatorial gradi......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
Circulating tumor cells (CTCs) carry reliable clinical information for the diagnosis and treatment of cancer that is a malignant disease with a high m......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (12)
The current COVID-19 pandemic caused by a novel coronavirus SARS-CoV-2 urgently calls for a working therapeutic. Here, we report a computation-based w......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (3)
This study presents the first example of the Pd-catalyzed cascade reactions of S-oxohexanenitrile with arylboronic acids, affording important synthon ......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (5)
In this research, machine learning including the genetic algorithm (GA) and support vector machine (SVM) algorithm is used to solve the "low up-conver......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (5)
Cerium(III) triflate-catalyzed multicomponent reactions between alkynyl carboxylic acids, tert-butyl isocyanide, and organic azides have been develope......
期刊： ACS COMBINATORIAL SCIENCE, 2020; 22 (9)
New 8-chloro-2-phenyl-2,7-naphthyridin-1(2H)-one building blocks bearing diverse substitutes on the 2-phenyl group were synthesized via an efficient d......
期刊： ACS COMBINATORIAL SCIENCE, 2019; 21 (2)
To develop a novel light-up probe and DNAzyme, we selected aptamers for N-methyl mesoporphyrin IX (NMM), a common fluorogenic analogue of coenzyme hem......
期刊： ACS COMBINATORIAL SCIENCE, 2019; 21 (3)
A highly regioselective acid-catalyzed three component reaction of 2-aminopyridine and 3-phenylpropiolaldehyde for the construction of imidazo[1,2-a]p......
期刊： ACS COMBINATORIAL SCIENCE, 2019; 21 (12)
The combinatorial materials chip approach is vastly superior to the conventional one that characterizes one sample at a time in the efficiency of comp......
期刊： ACS COMBINATORIAL SCIENCE, 2019; 21 (5)
DNA-encoded chemical libraries (DELs) have become an important ligand discovery technology in biomedical research and drug discovery. DELs can be comp......
期刊： ACS COMBINATORIAL SCIENCE, 2019; 21 (8)
An efficient and general carbonylative procedure for the synthesis of 3,4-dihydroquinazolin-2(1H)-one from 1-(halomethyl)-2-nitrobenzenes and aryl/alk......
