Total Synthesis of Semaglutide Based on a Soluble Hydrophobic-Support-Assisted Liquid-Phase Synthetic Method

Liu, XB; Zhang, N; Gu, XT; Qin, YH; Song, D; Zhang, L; Ma, ST

Ma, ST (corresponding author), Shandong Univ, Dept Med Chem, Sch Pharmaceut Sci, Key Lab Chem Biol,Minist Educ,Cheeloo Coll Med, Jinan 250012, Peoples R China.

ACS COMBINATORIAL SCIENCE, 2020; 22 (12): 821

Abstract

Considering the high cost of the production of semaglutide, which is currently the most promising antidiabetic drug especially for the treatment of ty......

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