筛选条件 共查询到500条结果
排序方式
Bioconjugation of Au25 Nanocluster to Monoclonal Antibody at Tryptophan

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (4)

We report the first bioconjugation of Au25 nanocluster to a monoclonal antibody at scarcely exposed tryptophan (Trp) residues toward the development o......

Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (7)

Membrane interactionconstitutes to be an essential parameter inthe mode of action of entities such as proteins, as well as cell-penetratingand antimic......

Semisynthetic Pneumococcal Glycoconjugate Nanovaccine

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (9)

Pneumococcal conjugate vaccines offer an excellent safety profile and high protection against the serotypes comprised in the vaccine. However, inclusi......

Development of Radiopharmaceuticals for NPY Receptor-5 (Y5) Nuclear Imaging in Tumors by Synthesis of Specific Agonists and Investigation of Their Binding Mode

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (11)

The neuropeptide-Y (NPY) family acts through four G protein-coupledreceptor subtypes in humans, namely, Y-1, Y-2,Y-4, and Y-5. A growing body of evide......

Surface Functionalization and Reversible Disassembly of DNA-Assembly Nanoparticles for Sensitive and Multiplexed Detection of DNA Targets Without Enzymatic and Catalytic Amplification

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (6)

Recently, DNA-assembly nanoparticles based on DNA-metalion interactionsare emerging as new building blocks for drug delivery and metal nanostructuresy......

mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (12)

Phosphorodiamidate morpholino oligomers (PMOs) are a special type of antisense oligonucleotides (ASOs) that can be used as therapeutic modulators of p......

Tyrosinase-Related Protein2 Peptide with Replacement of N-Terminus Residue by Cysteine Binds to H-2Kb and Induces Antigen-Specific Cytotoxic T Lymphocytes after Conjugation with CpG-DNA

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (2)

Recent studies have shown the potent efficacy of peptide-based vaccines for cancer immunotherapy. Immunological performance is optimized through the c......

A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga- DOTA-TATE Derivatives

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (3)

Recently, several radiometalated peptides have been approved for clinical imaging and/or therapy (theranostics) of several types of cancer; nonetheles......

Synthesis and Biological Evaluation of Peptide-Adjuvant Conjugate Vaccines with Increasing Antigen Content

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (4)

Synthetic vaccines that induce T cell responses to peptide epitopes are a promising immunotherapy for both communicable and noncommunicable diseases. ......

Dynamics of DNA Origami Lattices

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (1)

Hierarchical assembly of programmable DNA frameworks -such as DNA origami -paves the way for versatile nanometer-precise parallel nanopatterning up to......

Propensities of Fatty Acid-Modified ASOs: Self-Assembly vs Albumin Binding

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (5)

We conducted a biophysical study to investigate the self-assembling and albumin-binding propensities of a series of fatty acid-modified locked nucleic......

Peptide Bispecifics Inhibiting HIV-1 Infection by an Orthogonal Chemical and Supramolecular Strategy

期刊: BIOCONJUGATE CHEMISTRY, 2023; 34 (9)

Viral infections pose a significant threat to human health, and effective antiviral strategies are urgently needed. Antiviral peptides have emerged as......

共500条页码: 1/34页15条/页