Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria

Breine, A; Van Holsbeeck, K; Martin, C; Gonzalez, S; Mannes, M; Pardon, E; Steyaert, J; Remaut, H; Ballet, S; van der Henst, C

van der Henst, C (通讯作者),Flanders Inst Biotechnol, VIB VUB Ctr Struct Biol, VIB, Microbial Resistance & Drug Discovery, B-1050 Brussels, Belgium.;van der Henst, C (通讯作者),Vrije Univ Brussel, Struct Biol Brussels, B-1050 Brussels, Belgium.;Ballet, S (通讯作者),Vrije Univ Brussel, Res Grp Organ Chem, B-1050 Brussels, Belgium.

BIOCONJUGATE CHEMISTRY, 2023; 34 (7): 1234

Abstract

Membrane interactionconstitutes to be an essential parameter inthe mode of action of entities such as proteins, as well as cell-penetratingand antimic......

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