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Efficacy of prophylactic methylprednisolone on reducing the risk of post-extubation stridor in patients after an emergency intubation: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

BackgroundPost-extubation stridor (PES) is one of the most common complications of invasive respiratory support, with severe cases leading to possible......

Impact and cost-effectiveness evaluation of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

BackgroundHearing loss is quite prevalent and can be related to people's quality of life. To our knowledge, there are limited studies assessing the ef......

The cerebral mechanism of acupuncture for chronic insomnia with gastrointestinal disorder: protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background: Many patients with chronic insomnia disorder (CID) have gastrointestinal (GI) symptoms. First-line insomnia medications do not treat GI pr......

The efficacy of Tuina with herbal ointment for patients with post-stroke depression: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

BackgroundPost-stroke depression (PSD) is a common complication after stroke which hinders functional recovery and return to social participation of s......

Efficacy and safety of the Chinese herbal formula Hewei Jiangni recipe for NERD with cold-heat complex syndrome: study protocol for a double-blinded randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background Proton pump inhibitor (PPI) is effective for the treatment of nonerosive gastroesophageal reflux (NERD), but long-term use of PPI is prone ......

Effects of controlled hypotension with restrictive transfusion on intraoperative blood loss and systemic oxygen metabolism in elderly patients who underwent lumbar fusion

期刊: TRIALS, 2021; 22 (1)

BackgroundThe effects of restrictive fluid therapy combined with controlled hypotension in the elderly on systemic oxygen metabolism and renal functio......

Effects of salvianolate on microcirculatory disturbance in patients with stable coronary heart disease: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

BackgroundObstruction of coronary microcirculation can lead to myocardial ischemia and poor prognosis. Salvianolate exerts cardiovascular protection a......

Ultrasound-guided erector spinae plane block versus thoracic paravertebral block on postoperative analgesia after laparoscopic nephroureterectomy: study protocol of a randomized, double-blinded, non-inferiority design trial

期刊: TRIALS, 2021; 22 (1)

Introduction: Erector spinae plane block (ESPB) is a novel inter-fascial plane block, which is applied more and more in postoperative pain control, es......

Effectiveness of the Elos 2.0 prevention programme for the reduction of problem behaviours and promotion of social skills in schoolchildren: study protocol for a cluster-randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background: Early interventions benefit the mental health, academic performance and productivity of children and adolescents throughout their life. Th......

Efficacy and central mechanism of acupuncture treatment in patients with neck pain: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background: Acupuncture is effective for reducing the symptoms of neck pain (NP). However, the underlying mechanisms are not fully elucidated. Based o......

Effect of 'hand and foot acupuncture with twelve needles' on hemiplegia patients with 'qi deficiency and blood stasis' syndrome in the convalescent stage of Ischaemic stroke: study protocol for a randomised controlled trial

期刊: TRIALS, 2021; 22 (1)

Background Hemiplegia is a common sequela after stroke, and acupuncture is one of the most common physical therapies used to treat hemiplegia during t......

Efficacy of low-load resistance training combined with blood flow restriction vs. high-load resistance training on sarcopenia among community-dwelling older Chinese people: study protocol for a 3-arm randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background: Sarcopenia is accompanied by a decline in muscle mass, muscle strength, and muscle function. Resistance training is the most potential tra......

Efficacy of Yijinjing combined with Tuina for patients with non-specific chronic neck pain: study protocol for a randomized controlled trial

期刊: TRIALS, 2021; 22 (1)

Background: Non-specific chronic neck pain (NCNP) is a common musculoskeletal disorder which has caused a huge economic burden due to its expensive he......

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