期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Alzheimer's disease (AD) is an evolving challenge that places an enormous burden on families and society. The presence of obvious brain beta-amyloid (......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Intervertebral disc degeneration (IDD) is highly ubiquitous in the aged population and is an essential factor for low back pain and spinal disability.......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Myocardial infarction (MI) is the most common cause of heart failure (HF) worldwide. The aim of this study was to investigate the role of Klotho in ca......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 204 ()
A bivariate genome-wide association study was conducted in 137 pairs of twins to explore the shared genetic loci between cognition and blood pressure ......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Bone defects resulting from trauma, bone tumors, infections and skeletal abnormalities are a common osteo-porotic condition with respect to clinical t......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 202 ()
Sarcopenia is the age-related decrease in skeletal muscle mass, and current therapies for this disease are ineffective. We previously showed that ilea......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 205 ()
Osteoarthritis (OA) is an age-related chronic degenerative disease, and chondrocyte senescence has been established to play an important role in the p......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Microplastic pollution has attracted growing attention due to its prevalent and persistent exposure to general population through the food chain, but ......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 202 ()
Aging is a process involving physiological changes that lead to the decline of biological functions of various tissues and organs of the body. Therefo......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 205 ()
Skin aging is characterized by a wide range of physiological and structural changes, including wrinkling, dyschromia, and roughness, as well as the re......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 204 ()
Nicotinamide adenine dinucleotide (NAD+) plays vital roles in cell metabolism, cell signaling, and gene expression regulation. NAD+ shows intricate su......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2021; 197 ()
We have reported that pseudoginsenoside-F11 (PF11) can significantly improve the cognitive impairments in several Alzheimer's disease (AD) models, but......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2021; 196 ()
Kidney ageing, which is always accompanied by renal fibrosis, drives the progression of renal fibrosis. Thioredoxin-interacting protein (TXNIP) is an ......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2021; 194 ()
Advanced age is the major risk factor for idiopathic Parkinson's disease (PD), but to date the biological relationship between PD and ageing remains e......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2021; 195 ()
Alzheimer?s disease (AD) is the most common cause of dementia globally. AD is a progressive neurodegenerative disorder, eventually manifesting as seve......