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A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (9)

Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) is an efficient tool for establishing genetic mode......

JIF:4.142

CD44 v5 domain inhibition represses the polarization of Th2 cells by interfering with the IL-4/IL-4R signaling pathway

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (1)

The balance between T helper type 1 (Th1) and T helper type 2 (Th2) cells is critical for both innate and acquired immune reactions. However, the prec......

JIF:4.142

Amino acid metabolism: challenges and opportunities for the therapeutic treatment of leukemia and lymphoma

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (7)

Leukemia and lymphoma-the most common hematological malignant diseases-are often accompanied by complications such as drug resistance, refractory dise......

JIF:4.142

The circadian clock sets a spatial-temporal window for recent thymic emigrants

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (9)

The diurnal timing system regulates multiple functions of lymphocytes in peripheral lymphoid organs. Whether T-cell development in the thymus and T-ce......

JIF:4.142

METTL3 inhibition reduces N-6-methyladenosine levels and prevents allogeneic CD4(+) T-cell responses

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (9)

Alloreactive CD4(+) T cells play a central role in allograft rejection. However, the post-transcriptional regulation of the effector program in allore......

JIF:4.142

The onset, development and pathogenesis of severe neutrophilic asthma

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (3)

Bronchial asthma is divided into Th2 high, Th2 low and mixed types. The Th2 high type is dominated by eosinophils while the Th2 low type is divided in......

JIF:4.142

Chloride intercellular channel 3 suppression-mediated macrophage polarization: a potential indicator of poor prognosis of hepatitis B virus-related acute-on-chronic liver failure

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (5)

Patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) are characterized by immune paralysis and susceptibility to infectio......

JIF:4.142

Giardia lamblia regulates the production of proinflammatory cytokines through activating the NOD2-Rip2-ROS signaling pathway in mouse macrophages

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (6)

Giardia lamblia is a zoonotic protozoan that causes the diarrheal illness giardiasis, with the highest prevalence reported in the tropics and subtropi......

JIF:4.142

The balance of interleukin-12 and interleukin-23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (7)

Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells mediating protection against bacterial infection through recogni......

JIF:4.142

Improvement of human myeloid and natural killer cell development in humanized mice via hydrodynamic injection of transposon plasmids containing multiple human cytokine genes

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (8)

Humanized mice reconstituted with a functional human immune system (HIS) are instrumental in studying human immunity and immune disorders in vivo. The......

JIF:4.142

T-lymphocyte subtyping: an early warning and a potential prognostic indicator of active cytomegalovirus infection in patients with sepsis

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (10)

Cytomegalovirus (CMV) infection is very common in patients suffering from sepsis and may cause poor prognosis. To explore the relationship between imm......

JIF:4.142

Human transitional and IgM(low) mature naive B cells preserve permissive B-cell receptors

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2021; 99 (8)

The level of immunoglobulin M (IgM) displayed on the surface of peripheral blood B cells exhibits a broad dynamic range and has been associated with b......

P300/CBP-associated factor (PCAF) attenuated M1 macrophage inflammatory responses possibly through KLF2 and KLF4

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2021; 99 (7)

Macrophages exhibit distinct phenotypes in response to environmental signals. The polarization of M1 macrophages plays an essential role in the inflam......

A preliminary investigation into the immune cell landscape of schistosome-associated liver fibrosis in humans

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2021; 99 (8)

Schistosomiasis is a widespread helminth disease that poses a heavy social and economic burden on people worldwide. Advanced schistosomiasis often dev......

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