Improvement of human myeloid and natural killer cell development in humanized mice via hydrodynamic injection of transposon plasmids containing multiple human cytokine genes

Tan, SL; Fang, MH; Fan, W; Wang, ZW; Lv, YA; Zou, J; Wang, X; Liu, B; Yang, YG; Hu, Z

Yang, YG; Hu, Z (通讯作者),First Hosp Jilin Univ, Minist Educ, Key Lab Organ Regenerat & Transplantat, Changchun 130061, Peoples R China.

IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (8): 624

Abstract

Humanized mice reconstituted with a functional human immune system (HIS) are instrumental in studying human immunity and immune disorders in vivo. The......

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