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A single residue deletion in the barley HKT1;5 P189 variant restores plasma membrane localisation but not Na+ conductance

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (10)

Leaf Na+ exclusion, mediated by plasma membrane-localised Class 1 High-affinity potassium (K+) Transporters (HKTs), is a key mechanism contributing to......

Characterization of modeled inhibitory binding sites on isoform one of the Na+/H- exchanger

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (9)

Mammalian Na+/H+ exchanger isoform one (NHE1) is a plasma membrane protein responsible for pH regulation in mammalian cells. Excess activity of the pr......

Interplay between human islet amyloid polypeptide aggregates and micro-heterogeneous membranes

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (11)

Human islet amyloid polypeptides (hIAPP) aggregate into amyloid deposits in the pancreatic islets of Langerhans, contributing to the loss of beta-cell......

Investigation of antibiofilm activity, antibacterial activity, and mechanistic studies of an amphiphilic peptide against Acinetobacter baumannii

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (6)

Biofilm-producing pathogens, such as Acinetobacter baumannii, have aroused escalating attention. Because these bacteria could secrete mixture with clo......

Potent in vitro synergistic antibacterial activity of natural amphiphilic Sapindoside A and B against Cutibacterium acnes with destructive effect on bacterial membrane

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (11)

Sapindus saponins are obtained from the outer bark of Sapindus mukorossi Gaertn. (S. mukorossi), and they have become an interesting subject in the se......

Substrate-dependent arrangements of the subunits of the BAM complex determined by neutron reflectometry

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (9)

In Gram-negative bacteria, the beta-barrel assembly machinery (BAM) complex catalyses the assembly of beta-barrel proteins into the outer membrane, an......

Function-related asymmetry of the specific cardiolipin binding sites on the mitochondrial ADP/ATP carrier

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (1)

The ADP/ATP carrier (AAC) transports matrix ATP and cytosolic ADP across the inner mitochondrial membrane (IMM). It is well known that cardiolipin (CL......

Secondary structure and transmembrane topology analysis of the N-terminal domain of the inner membrane protein EccE(1) from M. smegmatis using site-directed spin labeling EPR

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (2)

Protein EccE(1) is an essential component of the mycobacterial ESX-1 secretion system, which plays a crucial part in the process of virulence factors ......

Membrane nanodomains homeostasis during propofol anesthesia as function of dosage and temperature

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (2)

Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, ......

Study on the interaction mechanism of phospholipid imbalance and endoplasmic reticulum protein secretion imbalance in Aspergillus niger

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (3)

As the largest membrane organelle, the endoplasmic reticulum (ER) is the main location for protein preliminary processing and phospholipid synthesis. ......

Leucine heptad motifs within transmembrane domains affect function and oligomerization of human organic anion transporting polypeptide 1B1

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (4)

Organic anion transporting polypeptides (OATPs) are transmembrane proteins responsible for the uptake of a wide range of endogenous compounds and clin......

Lipid domain formation and non-lamellar structures associated with varied lysylphosphatidylglycerol analogue content in a model Staphylococcal plasma membrane

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2021; 1863 (5)

Dipalmitoyl-3-aza-dehydroxy-lysylphosphatidylglycerol (DP3adLPG), is a chemically stable synthetic analogue of the bacterial lipid lysylphosphatidylgl......

Idiopathic pulmonary fibrosis is associated with tight junction protein alterations

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2020; 1862 (5)

Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by an abnormal healing response to injury of the alveolar epithelium. Tight jun......

Investigation of the interactions between flavonoids and human organic anion transporting polypeptide 1B1 using fluorescent substrate and 3D-QSAR analysis

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2020; 1862 (5)

Organic anion transporting polypeptide 1B1 (OATP1B1) is a key hepatic uptake transporter whose inhibition could lead to adverse drug-drug and drug-foo......

Interpretation of the molecular mechanism of the electroporation induced by symmetrical bipolar picosecond pulse trains

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2020; 1862 (5)

Picosecond pulse trains (psPTs) are emerging as a new characteristic diagnostic and therapeutic tool in biomedical fields. To specifically determine t......

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