Investigation of the interactions between flavonoids and human organic anion transporting polypeptide 1B1 using fluorescent substrate and 3D-QSAR analysis

Xiang, YQ; Liu, S; Yang, JJ; Wang, ZM; Zhang, HJ; Gui, CS

Zhang, HJ; Gui, CS (corresponding author), Soochow Univ, Coll Pharmaceut Sci, 199 Renai Rd,Suzhou Ind Pk, Suzhou 215123, Jiangsu, Peoples R China.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2020; 1862 (5):

Abstract

Organic anion transporting polypeptide 1B1 (OATP1B1) is a key hepatic uptake transporter whose inhibition could lead to adverse drug-drug and drug-foo......

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