Copper-Catalyzed Deaminative Difluoromethylation

Zeng, XJ; Yan, WH; Zacate, SB; Cai, AJ; Wang, YF; Yang, DQ; Yang, KD; Liu, W

Liu, W (corresponding author), Miami Univ, Dept Chem & Biochem, Oxford, OH 45056 USA.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020; 59 (38): 16398

Abstract

The difluoromethyl group (CF2H) is considered to be a lipophilic and metabolically stable bioisostere of an amino (NH2) group. Therefore, methods that......

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