Copper-Catalyzed Decarboxylative Difluoromethylation

Zeng, XJ; Yan, WH; Zacate, SB; Chao, TH; Sun, XD; Cao, Z; Bradford, KGE; Paeth, M; Tyndall, SB; Yang, KD; Kuo, TC; Cheng, MJ; Liu, W

Liu, W (reprint author), Miami Univ, Dept Chem & Biochem, Oxford, OH 45056 USA.; Cao, Z (reprint author), Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Shanxi, Peoples R China.; Cao, Z (reprint author), Synfuels China Techn

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019; 141 (29): 11398

Abstract

We report herein a highly efficient Cu-catalyzed protocol for the conversion of aliphatic carboxylic acids to the corresponding difluoromethylated ana......

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