Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers

Ochsner, UA; Green, LS; Rice, TP; Olivas, E; Janjic, N; Katilius, E

Janjic, N (reprint author), SomaLogic Inc, 2945 Wilderness Pl, Boulder, CO 80301 USA.

BIOCHEMISTRY, 2019; 58 (46): 4632

Abstract

The mature forms of the TGF-beta family members GDF-11 and GDF-8 are highly similar 25 kDa homodimers with 90% amino acid sequence identity and 99% si......

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