TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites

DeNizio, JE; Dow, BJ; Serrano, JC; Ghanty, U; Drohat, AC; Kohli, RM

Kohli, RM (corresponding author), Perelman Sch Med, Dept Med, Dept Biochem & Biophys, Philadelphia, PA 19147 USA.; Drohat, AC (corresponding author), Univ Maryland, Dept Biochem & Mol Biol, Sch Med, Baltimore, MD 21201 USA.

JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (8):

Abstract

In mammalian genomes, cytosine methylation occurs predominantly at CG (or CpG) dinucleotide contexts. As part of dynamic epigenetic regulation, 5-meth......

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