Inefficient V(D)J recombination underlies monogenic T cell receptor beta expression

Wu, GS; Bassing, CH

Bassing, CH (corresponding author), Univ Penn, Perelman Sch Med, Immunol Grad Grp, Philadelphia, PA 19104 USA.; Bassing, CH (corresponding author), Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (31): 18172

Abstract

The assembly of T cell receptor (TCR) and immunoglobulin (Ig) genes by V(D)J recombination generates the antigen receptor (AgR) diversity that is vita......

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