Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan

Marini, I; Zlamal, J; Faul, C; Holzer, U; Hammer, S; Pelzl, L; Bethge, W; Althaus, K; Bakchoul, T

Bakchoul, T (corresponding author), Univ Hosp Tubingen, Med Fac Tubingen, Transfus Med, Tubingen, Germany.; Bakchoul, T (corresponding author), Univ Hosp Tubingen, Ctr Clin Transfus Med, Tubingen, Germany.

HAEMATOLOGICA, 2021; 106 (1): 196

Abstract

Immune thrombocytopenia is a common bleeding disease caused by autoantibody-mediated accelerated platelet clearance and impaired thrombopoiesis. Accum......

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