InsP(3)R-RyR Ca2+ channel crosstalk facilitates arrhythmias in the failing human ventricle

Jin, X; Amoni, M; Gilbert, G; Dries, E; Puertas, RD; Tomar, A; Nagaraju, CK; Pradhan, A; Yule, DI; Martens, T; Menten, R; Vanden Berghe, P; Rega, F; Sipido, K; Roderick, HL

Roderick, HL (通讯作者),Katholieke Univ Leuven, Lab Expt Cardiol, Dept Cardiovasc Sci, B-3000 Leuven, Belgium.

BASIC RESEARCH IN CARDIOLOGY, 2022; 117 (1):

Abstract

Dysregulated intracellular Ca2+ handling involving altered Ca2+ release from intracellular stores via RyR channels underlies both arrhythmias and redu......

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