ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining

Lu, HM; Zhang, Q; Laverty, DJ; Puncheon, AC; Augustine, MM; Williams, GJ; Nagel, ZD; Chen, BPC; Davis, AJ

Davis, AJ (通讯作者),UT Southwestern Med Ctr, Dept Radiat Oncol, Dallas, TX 75390 USA.

NUCLEIC ACIDS RESEARCH, 2023; 51 (13): 6770

Abstract

Ataxia-telangiectasia mutated (ATM) drives the DNA damage response via modulation of multiple signal transduction and DNA repair pathways. Previously,......

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