PARP Activity Fine-tunes the DNA Replication Choreography of Chk1-depleted Cells

Calzetta, NL; Besteiro, MAG; Gottifredi, V

Besteiro, MAG; Gottifredi, V (corresponding author), Consejo Invest Cient & Tecn, Fdn Inst Leloir, Inst Invest Bioquim Buenos Aires, Ave Patricias Argentinas 435,C1405BWE, Buenos Aires, DF, Argentina.

JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (10):

Abstract

Checkpoint Kinase 1 (Chk1) prevents DNA damage by adjusting the replication choreography in the face of replication stress. Chk1 depletion provokes sl......

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