(N)ucleolar localization of RAG1 modulates V(D)J recombination activity

Brecht, RM; Liu, CC; Beilinson, HA; Khitun, A; Slavoff, SA; Schatz, DG

Schatz, DG (corresponding author), Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06529 USA.; Schatz, DG (corresponding author), Yale Sch Med, Dept Immunobiol, New Haven, CT 06511 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (8): 4300

Abstract

V(D)J recombination assembles and diversifies Ig and T cell receptor genes in developing B and T lymphocytes. The reaction is initiated by the RAG1-RA......

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